Module 8 Flashcards

Cellular ATP and Protein Synthesis

1
Q

what is the relative speed of cytoplasm

A

very fast

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2
Q

what is the relative speed of mitochondria

A

slower

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3
Q

what is the substrates of cytoplasm

A

glucose

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4
Q

what is the substrates of mitochondria

A

pyruvate

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5
Q

what is the number of ATP formed in the cytoplasm

A

2

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6
Q

what is the number of ATP formed in the mitochondria

A

32-34 ATP (flexible)

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7
Q

what is the by-product of glucose decomposition and ATP synthesis in cytoplasm

A

pyruvate

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8
Q

what is the by-product of glucose decomposition and ATP synthesis in mitochondria

A

CO2 and H2O

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9
Q

what site is aerobic

A

mitochondria

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10
Q

what cite is anaerobic

A

cytoplasm

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11
Q

what is pyruvate

A

by product of glycolysis

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12
Q

what is pyruvate’s fate

A

moved into the mitochondria and it continue to break it down

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13
Q

how many pyruvates are produced by glycolysis of 1 glucose molecule

A

2

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14
Q

what is lactate

A

breakdown of glycolysis turn pyruvate into lactate

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15
Q

why is lactate produced

A

maintain glycolysis by turning it into lactate

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16
Q

why is lactate associated with metabolic acidosis

A

when ATP use exceeds TCA which usually uses the H+ to diffuse superoxide

17
Q

what is the process of producing ATP anaerobically called

A

glycolysis

18
Q

what is the process of producing ATP aerobically called

A

oxidative phosphorylation

19
Q

what are the two steps of Aerobic ATP production called

A

1: (Krebs cycle), finish decomposing pyruvate, produces carbon dioxide
2: (Electron transport train), strip electrons from HADH and FADH2, produces water and ATP is made

20
Q

what step is O2 used in

A

step 2 (electron transport train)

21
Q

what by-product of aerobic metabolism of O2 produce

A

Makes H2O from O2 and H

22
Q

what are the main cellular structures associated with protein synthesis

A

Nucleus: DNA and RNA
process: transcription
Ribosomes: mRNA and tRNA
process: translation

23
Q

what are the two types of ribosomes

A

Free and Rough Endoplasmic Reticulum (RER)

24
Q

what are the different types of ribosomes

A

mRNA: code for proteins amino acids
rRNA: structural part of ribosomes
tRNA: delivers amino acids to ribosomes

25
What are the different types of proteins made from each ribosome type?
Free: cytoskeleton, glycolytic enzyme RER: membrane channels, receptors, molecules stored and released from vesicles
26
what is the function of the Golgi apparatus
where RER proteins are modified and packaged and 'shipped' to destination
27
define transcription
mRNA 'copy' of DNA 'code' made in the nucleus
28
define translation
translate code to a new protein in the ribosome
29
where does transcription take place
nucleus
30
what is the product of translation
mRNA
31
where does translation take place
outside of the nucleus-ribosomes
32
what is the product of translation
primary sequence of protein
33
define GENE
segments within DNA strands containing the code for 1 protein
34
define triplet
a set of three DNA base CCT-CGA-TCA
35
define codon
a set of three complementary mRNA bases
36
define anticodon
a set of three tRNA bases
37
what are the two types of genetic mutations
substitution and deletion/insertion
38
what are the consequences to the proteins substitution code for
substituting one base for another-may or may not have damaging consequence on protein ( like misspelling a word with one letter wrong-we still know the word)
39
what are the consequences to the proteins deletion/insertion code for
when a base is deleted or added, it changes the base sequence from that triplet onward- and usually a fatal mutation