Modules 3-4 Flashcards

1
Q

Layers of digestive tract wall

A

mucosa-submucosa-muscularis-serosa

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2
Q

salivary glands and what do they secrete

A

parotid, sub-mandibular, sublingual - secrete saliva: lingual lipase, salivary amylase and lysozyme

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3
Q

sphincters at top and bottom of stomach

A

lower esophageal, pyloric

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4
Q

gastric juice

A

HCl, pepsinogen, mucus(secreted by stomach crypts), gastric lipase

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5
Q

Small intestine parts

A

duodenum, Jejunum, ileum

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6
Q

cells on surface of villi

A

enterocytes

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7
Q

where is the absorptive site in small intestine

A

in submucosa of villi in absorptive vessel

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8
Q

how is water absorbed

A

osmosis into blood

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9
Q

how are lipids and fat soluble vitamins absorbed

A

passive diffusion into lacteal in small intestine villi move into lymphatic vessels which drain into blood

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10
Q

how is fructose absorbed

A

facilitated diffusion with protein transporter into capillaries

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11
Q

how are glucose and amino acids absorbed

A

absorbed against concentration gradient using active transport

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12
Q

what does the lacteal eventually drain into

A

thoracic duct

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13
Q

what enzymes do the microvilli store

A

lactase, sucrase, maltase

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14
Q

Parts of Large intestine

A

cecum, ascending colon, transverse colon, descending colon, sigmoid colon

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15
Q

microbiome

A

large variety of non-human genetic material within body, the whole genome

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16
Q

microbiota

A

total composite of microorganisms found in body (mainly bacteria) in one area or whole body

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17
Q

pancreas endocrine function

A

insulin and glucagon

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18
Q

pancreas exocrine function

A

pancreatic juice

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19
Q

pancreatic juice contents

A

pancreatic amylase, pancreatic lipase, pancreatic proteases, bicarbonate

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20
Q

probiotics

A

living organisms yogurt kombucha

21
Q

prebiotics

A

not living organisms act as food for microbiome and support its function

22
Q

GERD

A

gastroesophageal reflux disease, can promote ulcers, weight loss can help, risk for leading to cancer is low

23
Q

gallstones

A

hardened bile deposits in gall bladder or bile duct, occurs because of too much cholesterol compared to bile salts in bile

24
Q

Diverticulitus

A

walls of digestive tract weaken and cause outpouchings on colon usually can lead to diverticulosis (bleeding of diverticula)

25
anabolism
build up molecules , require net input of energy
26
catabolism
break down molecules, lead to net release of energy
27
ATP structure
3 phosphate groups attached to an adenosine base, high energy bonds between phosphates
28
Main steps of glucose metabolism
glycolysis, breakdown of pyruvate, citric acid cycle, electron transport chain
29
glycolysis
6 carbon glucose is broken down into 2 molecules of 3 carbon pyruvate (+2 ATP), occurs in cytoplasm, can be anaerobic
30
anaerobic breakdown of pyruvate
pyruvate is oxidized into lactate 1 ATP is gained
31
aerobic metabolism of pyruvate
pyruvate and CoA form acetyl CoA , leads to loss of some e- captured by NADH+H+ and CO2 is released
32
how is citrate formed
acetyl CoA reacts with oxaloacetate
33
citric acid cycle
Acetyl CoA reactis with oxaloacetate to form citrate, citrate goes through reactions to form 8 different molecules some energy is captured in GTP, citric acid intermediates react to form next molecules in cycle e- are lost then captured by FADH+H+ and FADH2 which move to the membrane of mitochondia
34
electron transport chain (oxidative phosphorylation)
NADH+H+ and FADH2 exchange electrons with membrane bound proteins in series of redox reactions, creating an electrochemical gradient that leads to the creation of ATP using ATP synthase
35
how does ATP synthase work
promotes the bonding of phosphate group onto ADP
36
How much ATP is made in cellular respiration
30+
37
how much ATP is made in the breakdown of pyruvate
1 but only when its anaerobic and producing lactate
38
how much ATP is gained in glycolysis
2
39
when is acetyl CoA formed
at the beginning of the citric acid cycle
40
how is glycerol metabolized
can be converted to glucose then goes through all steps of cellular respiration
41
where is most lipid energy coming from
fatty acids
42
how are fatty acids metabolized
broken down 2 carbons at a time (beta-oxydation) to form acetyl CoA which combines with oxaloacetate form citrate to enter citric acid cycle
43
how are amino acids metabolized
removal of nitrogen group (deamination) there are 21 different possible products, remaining chains can either be made into glucose, pyruvate or citric acid intermediates
44
cellular respiration equation
c6+h12+06 + 6O2 -> 6CO2 + 6H2O
45
what is acetyl CoA made from
pyruvate and CoA make acetyl CoA
46
how is citrate made
from acetyl CoA and oxaloacetate
47
what does pyruvate turn into
Lactate or Acetyl CoA
48
Electron transporters
NADH+H+ and FADH2