MODY Flashcards
(11 cards)
1
Q
type of inheritance
A
autosomal dominant
2
Q
glucokinase pathophysiology
A
helps with glucose level recognition
if not working - body allows a higher glucose tolerance
3
Q
HNF 1 alpha pathophysiology
A
lowers amount of insulin produced by pancreas
4
Q
HNF 4 alpha pathophysiology
A
lowers amount of insulin produced
5
Q
HNF beta
A
lowers amount of insulin produced
6
Q
hallmark HNF 1 alpha
A
early 20s/ adolescence, most common
7
Q
hallmark HNF 2 alpha
A
low birth weight and low insulin at birth
8
Q
halmark HNF beta
A
renal cysts, uterine abnormalities, gout
later development of diabetes
9
Q
key features of MODY (2)
A
diabetes
10
Q
treatment of gluckokinase
A
dietary
11
Q
treatment of transcription factor
A
dietary, OHA, insulin
