Molecular Biology Flashcards

Study of the cells and biological molecules in the body (145 cards)

1
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Topics /Module Activities

Universal features of cell, techniques in cellular biology
1. Levels of biological organization
2. Techniques in cell biology (basic methods)
3. Differences between prokaryotic and eukaryotic cells

Macromolecules
1. The chemistry of life
2. Properties of water are essential in biology
3. Sugars/carbohydrates
4. Fats/lipids
5. Amino acids/protein
6. Nucleotides/nucleic acid

Cell structure and functional organizations
1. Organelles
2. Endoplasmic reticulum: proliferation and differentiation
3. Nucleus and nucleoli
4. Golgi reassembly and disassembly and protein trafficking
5. Lysosome
6. Peroxisome
7. Ribosomes
8. Clinical correlations
Energy conversion: mitochondria structure and function Membrane transport of small molecules and electrical properties of the membrane
1. The mitochondria structure and function
2. Cellular respiration/ATP Production in Mitochondria
3. Electron Transport Chain
4. Clinical correlation

Membrane structure and function
Bulk transport
1. The fluid Mosaic Model
2. Membrane proteins
3. Membrane Transport
4. Osmosis
5. Active and Passive Transport
6. Endocytosis and Exocytosis
7. Vesicle Formation and Transport
8. Clinical correlation

Cell communication
1. Cell signaling
2. Three stages of signaling: reception, transduction and response
3. Receptors and Ligands in cell signaling
4. First and second messengers
5. Clinical correlations

Cell cycle, Mitosis
1. Mitosis
2. The cell cycle
3. Regulation of the cell cycle
4. Clinical correlation

Cell death and survival
1. Apoptosis: the elimination of unwanted cells
2. Extrinsic pathway and cell surface death receptors
3. Intrinsic pathway and Bcl2 proteins
4. Extracellular survival factors that inhibit apoptosis
5. Clinical correlations

Cellular Reproduction and Meiosis
1. Stages of meiosis
2. Mitosis vs meiosis
3. Clinical considerations

DNA and RNA structure and function, genome organization and chromatin structure
1. Genome size organization
2. DNA packaging
3. Molecular structure of chromatin
4. Global perspective of chromosomes
5. Genomics- the future of healthcare and medicine

Genetic code, transcription and translation of genetic code
DNA repair mechanisms and disorders
1. Genes specify proteins via transcription and translation
2. Transcription: DNA directed synthesis of RNA
3. Eukaryotic cells modify RNA after transcription
4. molecular components of translation
5. translation: RNA directed synthesis of polypeptide
6. mutations can affect protein structure & function

Regulation of gene expression
Protein modifications and intracellular transport
1. Bacterial regulation of gene expression
2. Regulation of eukaryotic gene expression
3. The roles of non-coding RNAs
4. Cell differentiation & embryotic development
5. Completing and targeting the functional protein
6. Post translational modifications
7. Clinical considerations

Cancer
1. Cancer cells
2. Cancer epidemiology identifies preventable causes
3. Accumulation of mutations
4. Properties of cancer cells
5. Cancer-critical genes
Different types of cancers

Integrating cells to tissues & Extracellular Matrix (ECM) and Cell-Cell Interaction
4. Basic types of epithelial tissue
5. Tight junctions
6. Cytoskeleton-linked junctions
7. Gap junctions
8. Clinical correlations
9. ECM: overview: Ground substance, Fibers
10. Connective tissue: Cells and classification
11. Clinical correlations
Stem cells and tissue renewal
1. Different cell types make up tissues
2. Tissue renewal
3. Stem cells
4. Signals for stem cells
5. Use of stem cells to repair damaged tissue

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Activities

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6
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Universal features of cell, techniques in cellular biology

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Techniques in cell biology (basic methods)

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9
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Differences between prokaryotic and eukaryotic cells

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14
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Macromolecules

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16
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Properties of water are essential in biology

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17
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Sugars/carbohydrates

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18
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Fats/lipids

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19
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Amino acids/protein

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20
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Nucleotides/nucleic acid

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Cell structure and functional organizations
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Endoplasmic reticulum: proliferation and differentiation
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3
Nucleus and nucleoli
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4
Golgi reassembly and disassembly and protein trafficking
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5
Lysosome
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6
Peroxisome
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Ribosomes
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Clinical correlations
34
Energy conversion: mitochondria structure and function Membrane transport of small molecules and electrical properties of the membrane
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2
Cellular respiration/ATP Production in Mitochondria
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3
Electron Transport Chain
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4
Clinical correlation
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Membrane structure and function
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Bulk transport
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Membrane proteins
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3
Membrane Transport
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4
Osmosis
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5
Active and Passive Transport
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6
Endocytosis and Exocytosis
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7
Vesicle Formation and Transport
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8
Clinical correlation
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Cell communication
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Three stages of signaling: reception, transduction and response
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3
Receptors and Ligands in cell signaling
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4
First and second messengers
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5
Clinical correlations
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Cell cycle, Mitosis
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The cell cycle
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3
Regulation of the cell cycle
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4
Clinical correlation
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Cell death and survival
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Extrinsic pathway and cell surface death receptors
76
3
Intrinsic pathway and Bcl2 proteins
77
4
Extracellular survival factors that inhibit apoptosis
78
5
Clinical correlations
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Cellular Reproduction and Meiosis
81
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82
2
Mitosis vs meiosis
83
3
Clinical considerations
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DNA and RNA structure and function, genome organization and chromatin structure
88
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89
2
DNA packaging
90
3
Molecular structure of chromatin
91
4
Global perspective of chromosomes
92
5
Genomics- the future of healthcare and medicine
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Genetic code, transcription and translation of genetic code
98
DNA repair mechanisms and disorders
99
1
100
2
Transcription: DNA directed synthesis of RNA
101
3
Eukaryotic cells modify RNA after transcription
102
4
molecular components of translation
103
5
translation: RNA directed synthesis of polypeptide
104
6
mutations can affect protein structure & function
105
106
Regulation of gene expression
107
Protein modifications and intracellular transport
108
1
109
2
Regulation of eukaryotic gene expression
110
3
The roles of non-coding RNAs
111
4
Cell differentiation & embryotic development
112
5
Completing and targeting the functional protein
113
6
Post translational modifications
114
7
Clinical considerations
115
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Cancer
120
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121
2
Cancer epidemiology identifies preventable causes
122
3
Accumulation of mutations
123
4
Properties of cancer cells
124
5
Cancer-critical genes
125
Different types of cancers
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130
Integrating cells to tissues & Extracellular Matrix (ECM) and Cell-Cell Interaction
131
4
132
5
Tight junctions
133
6
Cytoskeleton-linked junctions
134
7
Gap junctions
135
8
Clinical correlations
136
9
ECM: overview: Ground substance, Fibers
137
10
Connective tissue: Cells and classification
138
11
Clinical correlations
139
Stem cells and tissue renewal
140
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141
2
Tissue renewal
142
3
Stem cells
143
4
Signals for stem cells
144
5
Use of stem cells to repair damaged tissue
145
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