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Cardiovascular Lectures > Molecular Biology: Lipoprotein Structure and Function > Flashcards

Molecular Biology: Lipoprotein Structure and Function Flashcards

1
Q

What lipoprotein is this?

A
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2
Q

Complete each step

A
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3
Q
  • Describe what the generation of, the TAG composition, the cholesterol composition, and function of:
    • HDL
    • LDL
A
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4
Q

What is the purpose of the LCAT enzyme?

What additional molecule does it need?

A

Convert cholesterol bound to HDL into cholesteryl ester using a lecithin molecule

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5
Q

HDL Mediates the Formation of LDL

What is happening from 1 to 4 in this figure?

A
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6
Q

Which apolipoprotein is associated with these?

A
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7
Q

Describe each step

A
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8
Q

What lipoprotein is this?

A
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9
Q

If a cell needs cholesterol, what are the two ways that it can get it?

A

Make it or increase LDL receptors

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10
Q

What are the two receptors in the liver that are able to bind chylomicron-remnants?

A
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11
Q

Which apolipoprotein is associated with chylomicrons and chylomicron remnants?

A
  • Top: chylomicron
  • Bottom: chylomicron remnants
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12
Q

What is CETP?

A
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13
Q

About ___% of Lipids in the blood is cholesterol, with ____ being actual cholesterol and _____ being esterified cholesterol

A
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14
Q

What lipoprotein is this?

A
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15
Q

What enzyme is described?

A
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16
Q
  • Describe what the generation of, the TAG composition, the cholesterol composition, and function of:
    • VLDL
    • Chylomicrons
A
17
Q

What lipoprotein is this?

A
18
Q

HDL Mediates the Formation of LDL

What is happening from 5 to 8 in this figure?

A
19
Q

About ___% of Lipids in the blood is triglycerides and ____% are phospholipids

A
20
Q
  • What must occur before Triglycerides can enter a cell?
    • What is the exception to this?
A
21
Q
  • What are the TRIACYLGLYCEROL carriers?
  • What are the CHOLESTEROL carriers?
A
22
Q

What is the function of Lipoprotein Lipase?

A
23
Q

About ____ % of fatty acids are bound to albumin

A
24
Q

What is the purpose of the ACAT enzyme?

A

Convert intracellular cholesterol to the cholesteryl ester

25
Q

What enzyme is described?

A
26
Q

What is the function of Hepatic Lipase?

A
27
Q

What goes on the outer regions of a protein and what goes in the inner regions?

A
  • Outer
    • Peripheral proteins
    • Phospholipids
    • Some nonesterified cholesterol may sick through the phospholipids
  • Inner
    • Integral proteins
    • Cholesteryl-ester
    • Triglycerides

Cardiovascular Lectures (27 decks)

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