Mood Disorders Flashcards

(40 cards)

1
Q

Definition of a Mood Disorder

A

Psychological disorder, characterised by the elevation/lowering of someones mood

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2
Q

Examples of Mood Disorders

A
Major Depressive Disorder 
Bipolar affective disorder
Seasonal affective disorder
Environmental Depression 
Premenstrual dysphoric disorder 
Cyclothymic disorders
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3
Q

Who are more affected by mood disorders and by how much

A

Females, 2:1 to males

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4
Q

What is the relative risk of getting a mood disorder if a 1st degree relative has it

A

2-3x

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5
Q

what age does a mood disorder most commonly come on in

A

12-24 or >65

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6
Q

Aetiology of Depression

A

mostly unknown, multi-factorial, although certain life events, stress and gender can play a part

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7
Q

Prognosis of depression

A

1/3 recurrence rate within 1 year
50% lifetime recurrence
87% of recurrence is within 15 years

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8
Q

Clinical features of Depression

A

3 Core symptoms:
Anhedonia
Anergy
Low mood

7 Other:
Disturbed sleep
Poor concentration 
psychomotor agitation/slowing
low self-confidence
changes to appetite
guilt/self-blame
suicidal ideation
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9
Q

Diagnostic criteria and classification for depression

A

Symptoms must be present most days, most of the time for at least 2 weeks

Mild - 4 symptoms (at least 2 core symptoms)
Moderate - 6 (at least 2 core symptoms)
Severe - 8 (has to be present for >4 weeks, with every symptom present for most of every day, at least 2 core symptoms)
Severe +Psychosis - all features of severe + psychosis

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10
Q

Differentials for Depression

A
Bipolar
Schizophrenia
Grief reaction
Dementia
Anxiety
Hypothyroidism
Vit B12 deficiency 
ADR
Sleep apnoea 
Cushings
MS
Parkinsons
Infection
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11
Q

How do you investigate suspected depression

A

Thorough Mental health history asking about all the symptoms of depression - (questionnaire PHQ-9)

Bloods - FBC, TFT, metabolic screen, 24-hr cortisol, folic acid, Tox screen, B12, fasting glucose

collateral history

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12
Q

What is somatic syndrome

A

Physical or biological symptoms of depression

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13
Q

Symptoms of somatic syndrome

A
decreased appetite
weight loss
early morning waking
diurnal variation in mood -wose in morning 
decreased libido
psychomotor retardation 
emotional reactivity
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14
Q

How does the presence of a mood disorder modulate the risks of self harm

A

vastly increased

36-90% of suicides are by people with depression
5-15% of patients with a diagnosis of depression die from suicide

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15
Q

what gender more commonly self harms and by how much

A

F>M 2:1

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16
Q

How does marital status affect self harming

A

Divorced > single > widowed > married

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17
Q

what age is self harm most common in

18
Q

what is the most popular form of self harm

A

cutting or overdose

19
Q

what factors predispose to repeated self harming

A
Personal History 
Personality disorder diagnosis 
history of violence 
alcohol/drug misuse
being unmarried
20
Q

What factors indicate intent to commit suicide

A
isolation
planning
leaving a note
settling debts, leaving a will 
use of violent methods 
perceived lethality by patient
21
Q

What gender commits suicide more commonly and by how much

22
Q

What are some vulnerable groups for suicide

A
LGBTQ+ 
Prisoners 
Asylum seekers
Veterans 
Mental health patients
23
Q

What is the options for BioPsycoSocial management for depression

A
BIO 
antidepressants (1st line bio approach)
atypical antipsychotics 
lithium 
T3 augmentation 
ECT 

PSYCHO
psychoeducation
CBT
interpersonal therapy

SOCIAL
support for education, training and employment
housing support
carers
CPN
social inclusion
24
Q

What is the guideline for treating mild/moderate depression

A

1st line antidepressant + low intensive (e.g. self help) psychotherapy + social support
2nd line - alternative antidepressant
3rd line St Johns wort monotherapy

keep in primary care as long as not getting worse

25
what is the guideline for treating moderate/treatment resistant mild depression
Still keep primary care for the meantime Antidepressant + High-intensity psychotherapy (psychologist-led CBT) consider a secondary care referral
26
what is the guideline for treating severe/psychotic depression/severe self-neglect
Admission + Medication +high intensity psychosocial intervential + MDT approach + Crisis resolution at home treatment ECT if extremely treatment-resistant
27
Epidemiology of bipolar affective disorder
1% M=F occurs in late teens - early 20s usually
28
how long do manic/depressive episodes last in bipolar affective disorder generally
6 months
29
how many people with bipolar affective disorder go on to have a further episode of mood disturbance after an episode
90%
30
how many episodes over 25 years does the average person with bipolar affective disorder have
10
31
what is the increase in suicide risk for someone with bipolar affective disorder
20-30x
32
what are the features of hypomania
``` increased or unstable mood increased energy mild overspending increased sociability increased distractibility increased sexual energy decreased sleep ``` present for at least 4 days and at least 3 of these
33
what are the features of mania
``` irritable, increased mood increased activity reckless behavior disinhibition marked distractibility increased sexual energy absent/severely impaired sleep grandiosity flight of ideas (jumps from thought to thought but there is a link between them) ``` present for at least 7 days OR severe enough for admission
34
how do you diagnose bipolar affective disorder
At least 2 episodes of mood disturbance, mania, hypomania or depression, recurrent mania/hypomania can only be BAD
35
what are some common mimics of bipolar affective disorder
``` normal mood variation recurrent depressive disorder cyclothymia dysrhythmia depression in dysthymia ```
36
What are the features of mania with psychosis
Mania + delusions + Hallucinations Delusions are mood-congruent hallucinations are 2nd person and mood-congruent 10% suffer 1st rank symptoms of schizophrenia
37
How do you manage acute mania
stop any antidepressants consider lithium/vaproate/lamotrigine as mood stabiliser consider benzo as behaviour modification offer antipsychotics mental health act assessment consider IPC try and avoid making serious decisions whilst unwell
38
Bipolar Depression treatment
mood stabilisers (lithium/valproate/lamotrigine) antidepressant (only alongside antimanic agent) atypical antipsychotic CBT (esp. if mild/moderate) psychoeducation social support
39
what drug is first line in pregnancy for treating bipolar affective disorder
anti-psychotics (aripiprazole, olanzipine etc)
40
what monitoring is required for lithium
weekly lithium level bloods after initiating and after dose changes then every 3 months after then U+E and TFT every 6 months contraception required