MOSBYs Flashcards

(47 cards)

1
Q

what drugs may increase serum CO2 and HCO3-

A

aldosterone, barbiturates, bicarbonates, ethacrynic acid, hydrocortisone, loop diuretics, mercurial diuretics, steroids

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2
Q

what drugs may decrease CO2

A

methicillin, nitrofurantoin, paraldehyde, tetracycline, diuretics, triamterene

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3
Q

what are signs of hypochloremia

A

hyper excitability of nervous system and muscles, shallow breathing, hypotension, and tetany

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4
Q

what are signs of hyperchloremia

A

lethargy, weakness, and deep breathing

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5
Q

what are drugs that may increase serum chloride

A

acetazolamide, ammonium chloride, androgens, chlorothiazide, cortisone preparations, estrogens, guanethidine, hydrochlorothiazide, methyldopa, nonsteroidal anti-inflammatory drugs

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6
Q

what drugs may decrease blood chloride

A

aldosterone, bicarbonates, corticosteroids, cortisone, hydrocortisone, loop diuretics, thiazide diurettics, triamterene

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7
Q

what is the normal BUN ratio

A

between 6-25 with ideal at 15.5

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8
Q

what drugs may increase creatine

A

ACE inhibitors, ahminoglycosides, cimetidine, heavy metal chemotherapeutic agents, and other nephrotoxic drugs such as cephalosporins

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9
Q

what drugs may increase blood glucose levels

A

antidepressants, antipsychotics, beta-adrenergic blocking agents, corticosteroids, cyclosporine, IV dextrose infusion, dextrothyroxine, diazoxide, diuretics, epinephrine, estrogens, glucagon, isoniazid, lithium, niacin, phenothiazines, phenytoin, salicylates, triamterene

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10
Q

what is the normal intracellular potassium concentration

A

150 mEq/L

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11
Q

what is the normal serum potassium concentration

A

4 mEq/L

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12
Q

what are signs of hyperkalemia

A

irritability, nausea, vomiting, intestinal colic, diarrhea

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13
Q

what are signs of hypokalemia

A

decrease in contractility of smooth, skeletal and cardiac muscle

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14
Q

what are some drugs that may increase potassium level

A

aminocaproic acid, antibiotics, antineoplastic drugs, captopril, epinephrine, heparin, histamine, isoniazid, lithium, mannitol, potassium-sparing diuretics, potassium supplements and succinylcholine

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15
Q

what drugs may decrease potassium level

A

acetazolamide, aminosalicyclic acid, glucose infusions, amphotericin B, carbenicillin, cisplatin, diuretics, insulin, laxatives, lithium carbonate, penicillin G sodium, phenothiazines, salicyclates (aspirin)

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16
Q

what drugs may increase sodium level

A

anabolic steroids, antibiotics, carbenicillin, clonidine, corticosteroids, cough medicines, estrogens, laxatives, methyldopa, and oral contraceptives

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17
Q

what drugs may decrease sodium level

A

ACE inhibitors, captopril, carbamazepine, diuretics, haloperidol, heparin non steroidal anti-inflammatory drugs, sodium free IV fluids, sulfonylureas, triamterene, tricyclic antidepressants and vasopressin

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18
Q

what drugs may increase BUN

A

allopurinol, ahminoglycosides, cephalosporins, nephrotoxic drugs, propranolol, rifampin, spironolactone, tetracyclines, thiazide diuretics, triamterene

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19
Q

drugs that may decrease BUN

A

chloramphenicol and streptomycin

20
Q

what is the normal value for hematocrit in a male

21
Q

what is the normal value for hematocrit in female

22
Q

what drugs may decrease hematocrit

A

chloramphenicol and penicillin

23
Q

what do decreased values of hemoglobin indicate

24
Q

what do increased levels of hemoglobin indicate

A

erythrocytosis

25
what drugs may increase hemoglobin levels
gentamicin and methyldopa
26
what drugs may decrease hemoglobin
antibiotics, antineoplastic drugs, aspirin, indomethacin, rifampin and sulfonamides
27
what drugs may increase platelet count
estrogens and oral contraceptives
28
what is the normal RBC count for males
4.7-6.1
29
what is the normal RBC count for females
4.2-5.4
30
what drugs may increase RBC count
erythropoietin and gentamicin
31
what does MCV stand for
mean corpuscular volume
32
how do you calculate MCV
(hematocrit % X 10)/RBC
33
what does MCH stand for
mean corpuscular hemoglobin
34
how do you calculate MCH
(hemoglobin X 10)/RBC
35
what does MCHC stand for
mean corpuscular hemoglobin concentration
36
how do you calculate MCHC
(hemoglobin X 100)/ hematocrit
37
what drugs may increase MCV
azathioprine, phenytoin, and zidovudine
38
what disorder is a 3 q trisomy
cornelia de lange
39
what is the syndrome associated with X centromere dislocation
roberts
40
what are the syndromes associated with philadelphia chromosomal abnormality
chronic myelogenous leukemia and acute myelogenous leukemia
41
drugs that cause false positive HcG tests
anti-convulsants, antiparkinsonian drugs, hypnotics, and tranquilizers
42
what drugs give false negatives for HcG tests
diuretics and promethazine
43
what is tested with a double test maternal screen
measure hCG and alpha-fetoprotein
44
what is tested with a triple test maternal screen
measure hCG, AFP and estriol
45
what is tested with a quadruple test maternal screen
measures hCG, AFP, estriol and inhibin A
46
what normally secretes inhibin A
granulosa cells
47
what is included in a fully integrated maternal screen
measures AFP, estriol, fetal nuchal translucency, beta and total hCG and pregnancy-associated plasma protein-A