"Most Common" Flashcards
Most common pathway for initial dissemination of carcinomas
Lymphatic spread
Hematogenous spread is typical with sarcomas but is also seen with some carcinomas, what 2 organs are most frequently involved in hematogenous dissemination?
Liver
Lungs
3 most common tumor sites in terms of incidence and mortality in men according to American Cancer Society
Prostate
Lung
Colon/rectum
3 most common tumor sites in terms of incidence and mortality in women according to American Cancer Society
Lung
Breast
Colon/rectum
3 most common cancers in developing world in men vs. women (according to American Cancer Society)
Men: lung, stomach, liver
Women: breast, cervix, lung
Most common primary tumor/cancer in skin
Basal cell carcinoma
Squamous cell carcinoma
Melanoma
Most common primary tumor/cancer in oral cavity
Squamous cell carcinomas (often associated with HPV)
Most common primary tumor/cancer in head and neck
Squamous cell carcinoma
Most common primary tumor/cancer in lung
Adenocarcinomas
[Others include small-cell carcinomas, squamous cell carcinomas]
Most common primary tumor/cancer in bladder
Urothelial carcinoma (originates in transitional epithelium)
Most common primary tumor/cancer in testes
Germ cell tumors (embryonal carcinomas)
Most common primary tumor/cancer in prostate
Adenocarcinoma
Most common primary tumor/cancer in breast
Adenocarcinoma (most common type is infiltrating ductal carcinoma)
Most common primary tumor/cancer in ovaries
Serous cystadenocarcinomas (tend to be bilateral)
Most common carcinoma associated with VHL syndrome
Renal carcinomas
Most frequently mutated gene in cancer
TP53
Most frequent malignancy that results from ionizing radiation
Myeloid leukemia
[followed by thyroid cancer in young people, breast, lung, salivary gland, skin, bone, GI tract]
Most common cancer associated with Human T-cell leukemia virus type I (HTLV-1)
Adult T cell leukemia/lymphoma (ATLL)
Most common cancer associated with HPV 16 and 18
Squamous cell carcinomas of cervix, anogenital region, head and neck (tonsillar mucosa)
Most common cancers associated with EBV
African Burkitt lymphoma
B-cell lymphoma in immunosuppressed
Hodgkin lymphoma
Nasopharyngeal and gastric carcinomas
Most common endocrinopathy resulting from paraneoplastic syndrome; what types of cancer is it associated with?
Cushing syndrome - associated with small cell carcinoma of lung, pancreatic carcinoma, neural tumors
Most common paraneoplastic syndrome; what kinds of cancer is it associated with?
Hypercalcemia; associated with squamous cell carcinoma of lung, breast, and renal carcinomas, also ATLL
Virtually all burns are colonized by bacteria. What is the most common offender?
Pseudomonas aeruginosa
Most common form of PEM seen in african children weaned too early onto an exclusively carbohydrate-based diet
Kwarshiorkor
