Mouse immune system

Question 1

PAMPs

Answer 1

Pathogen associated molecular patterns, ex lipno polysaccharide, bacterial flagellin, single and double stranded RNA, and non methylated DNA

Question 2

PRRs

Answer 2

Pattern recognition receptors, TLRs, Nod-like receptors, and RIG-like receptors

Question 3

TLR4

Answer 3

recognizes LPS

Question 4

TLR3/7

Answer 4

ss and dsRNA

Question 5

TLR9

Answer 5

DNA

Question 6

Cells of the innate immune system

Answer 6

monocytes, macrophages, granulocytes, innate like lymphocyte populations one, 2, and 3 including natural killer cells

Question 7

Cells of the adaptive immune system

Answer 7

T&B lymphocytes, express a highly antigen specific receptor that has arisen through gene rearrangement

Question 8

CD4+ T cells

Answer 8

T helper cells, recognize peptides presented in MHC class 2 and promote B lymphocytes activation and activate and regulate cellular immune responses via secretion of differing cytokines

Question 9

CD8+ T cells

Answer 9

Recognized antigenic peptides presented in MHC class I and serve as cytotoxic cells during the cell mediated immune response where they can destroy infected cells

Question 10

B cell major function

Answer 10

Produce highly antigen specific immunoglobulin’s which combined in inactivate pathogens in toxins, activation of B cells can lead to their differentiation to plasma cells