Movement Disorders

Question 1

Progressive supranuclear palsy

Answer 1

Supranuclear ophthalmoplegia (vertical more than horizontal), axial rigidity, neck extension, impaired postural reflexes, neck extension, inability to look down

Question 2

corticobasal ganglionic degeneration

Answer 2

apraxia, cortical sensory impairment, alien-limb phenomenon, severe unilateral rigidity, stimulus-sensitive myoclonus

Question 3

diffuse lewy body disease

Answer 3

early dementia, prominent visual hallucinations, sensitivity to extrapyramidal side effects of antidopaminergic neuroleptic drugs

Question 4

vascular parkinsonism

Answer 4

lower half parkinsonism with rigidity in the legs and marked gait impairment, corticospinal tract dysfunction, pseudobulbar palsy

Question 5

multiple system atrophy

Answer 5

early and prominent features of autonomic dysfunction, evidence of corticospinal tract dysfunction, cerebellar signs, stimulus-sensitive myoclonus, vocal cord paresis

Question 6

stiff-person syndrome

Answer 6

fluctuating and progressive muscle rigidity
- stiffness of axial and trunk muscles spread to proximal limb muscles over time
“TIN MAN SYNDROME’

Question 7

meige syndrome

Answer 7

focal dystonia characterized by blepharospasm, forceful jaw opening, lip retraction, neck contractions, tongue thrusting
Tx: botulinum toxin

Question 8

olivopontocerebellar atrophy

Answer 8

progressive cerebellar ataxia, falls no weakness or atrophy