Movement of medications around the body

Question 1

What is the goal of drug absorption?

Answer 1

from its site of administration

into the body to

specific target organs and tissues

the ultimate goal is

reaching a therapeutic concentration

in the bloodstream!!

Question 2

What are the 2 mechanisms of medication absorption?

Answer 2

Active Transport

Passive diffusion

Question 3

Define: distribution of medication?

Answer 3

process by which a medication

moves throughout the body

Question 4

What is the PRIMARY distribution vehicle of drugs?

Answer 4

Blood

Question 5

What is biotransformation?

Answer 5

the manner in which the body

metabolizes medication

(first pass effect)

Question 6

What is excretion?

Answer 6

when the body eliminates the

remnants of the drug

Question 7

What are the three mechanisms of excretion in the kidneys?

Answer 7

glomerular filtration

tubular secretion

partial reabsorption

Question 8

What is the chronotropic effect on the cardiovascular system?

Answer 8

Changes heart rate

Question 9

What is the inotropic effect on the cardiovascular system?

Answer 9

changes the contractility of the heart

Question 10

What is the dromotropic effect on the cardiovascular system?

Answer 10

affects the conduction speed

in the AV node and

subsequently the rate of

the electrical impulses in

the heart