MRCP CANNOT REMEmber -PART 1 Flashcards

1
Q

side effects of lithium toxicity other than nephrotoxic and tremor ?

A

hyperparathyroiidism - leading to increased calcium
idiopathic intracranial hypertension
hypothyroidism
weight gain

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2
Q

lithium blood levels normally checked every ?

A

3 months

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3
Q

what contributes to lithium toxicity ? (OTHER THAN ACE AND ARB AND DEHYDRATION )

A

NSAID and metronidazole

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4
Q

features of bells palsy ?

A

FORHEAD IS AFFECTED
post auricular pain, dry eyes , hyperacusis

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5
Q

Mx of bells palsy ?

A

ALL PATINET’S SHOULD RECIEVE PREDNISLONE WITHIN 72 HOURS
if sever facial palsy then can add anti virals

ARTFICAL TEARS AND LUBRICANT TO PREVENT EXPOSURE KERATOPATHY

if no improvement in paralysis - ENT REFERRAL

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6
Q

bells palsy more common in ?

A

pregnant women

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7
Q

NOONAN SYNDROME defect in ?

A

chromosome 12 - AFFECTS MALES - AD

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8
Q

features of noonan syndrome

A

pulmonary valve stenosis
factor XI deficiency
ptosis
low set ears
triangular shaped face

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9
Q

myoclonic dystrophy features ?

A

AD
dysarthria
diabetes
distal TONIC muscle weakness
dysphagia

FRONTAL BALDING
PTOSIS
long haggard face
cataracts

cardiomyopathy - HEART BLOCK FIRST DEGREE

MILD MENTAL IMPAREMENT

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10
Q

S3 gallop heart sound heard in other than heart failure ?

A

constrictive pericarditis
and mitral regurgitation

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11
Q

thiazides affect which part of the distal convoluted tubule ?

A

proximal part of the DCT - in the sodium chloride channels

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12
Q

WHAT IS THE MANAGMNET OF cryptospordosis ?

A

NITAZOXANIDE - if immunodeficient such as HIV

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13
Q

features of pseudohypoparthyroidism ?

A

short 4th and 5th metacarpals
obesity
round face
learning difficulties
short stature

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14
Q

MX of pseudohypoparthyroidism ?

A

INFUSION OF PTH

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15
Q

other than atovaquone +proguanil (madrone) for the prophylaxis of malaria what other drugs are used ?

A

chloroquine
doxycycline
mefloquine

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16
Q

features of discoid lupus erythematous ?

A

follicular keratin plugs
raised rash - sometimes scaly
photosensitive to sunlight
lesion heal with ATROPHY SCARING AND PIGMENTATION

17
Q

MX od discoid lupus erythematous ?

A

TOPICAL PREDNSILONE
OR HYDROXYCLOROQUINE

18
Q

investigative features of antiphosoplipid syndrome ?

A

THROMBOCYTOPENIA
and PROLONGED APTT

19
Q

prophylaxis of antipholipid syndrome ?

A

primary prophylaxis - events not occurred
aspirin

event occurred - secondary prophylaxis
INR TARGET 2-3
warfarin life long

if reoccurring
increasie INR target to 3-4
LIFE LONG WARFARIN
AND CONSIDER ADDING ASPIRIN

if pregnant - low dose aspirin and LMWH

20
Q

adverse effects of ciprofloxacin ?

A

prolong QT
lower seizure threshold
and tendinopathy

21
Q

what are poor prognostic features of sarcoidosis other than absence of erythema nodosmun ?

A

black and african
insidious onset
symptoms more than 6 months
extrapulmonary - lupus pernio and splenomegaly
stage 3 and 4

22
Q

features of whipple disease ?

A

lymphadenopathy
hyperpigmentation
pleurisy / pericarditis
ophthalmoplegia

23
Q

what are the features of neurofibromatosis other then axillary and groin freckles ?

A

peripheral neurofibromas

IRISH HAMARTOMAS - litchi nodules

pheochromocytoma

24
Q

WHAT ARETHE FEATURES OF VON HIPPER LINDAU SYDROME - OTHER THAN CLEAR CELL CARCINOMA

A

ENDOLYMPHATIC SAC TUMORS
PHEOCHROMOCYTOMA
RENAL CYST
RETINAL HEMANGIOMA - WHICH CAN BE VITROUS HEMORRHAGES
CEREBELLAR HEMANGIOMA

25
Q

features of Tuberous sclerosis ?

A

RETINAL HAMARTOMAS
RHABDOMYOMA
POLYCSTIC KIDNEYS
RENAL ANGIOMYLIPOTOMA

26
Q

managmnet of Gillian bare syndrome ?

A

IVIG

27
Q

managmnet of myasthenia gravid ?

A

LONG ACTING ACETYLCHOLINESTRASE inhibtors - pyridostigmine

then prednisolone

azathioprine or ciclosporin

28
Q

exacerbating factors of myasthenia gravid other than beta blockers ?

A

penicillin
quinine
procainamide
phenytoin
gentamcin

29
Q

exacerbating factors of psoriasis ?other than beta blockers

A

alcohol
lithium
NSAIDS
ace

30
Q

drug inducing lupus ?

A

procainamide
hydralazine

Less common causes
isoniazid
phenytoin

31
Q

causes of erythema nodosum ? OTHER THAN TB / SARCOIDOSIS / PREGNANCY / INFLAMMATORY BWEL DISEASE

A

LYMPHOMA
BECHET DISEASE
STREPTOCOCCI
PENIILLIN
BRUCELLOSIS
SULPHONAMIDES
COCP