ms

Question 1

ms

Answer 1

chronic progressive neurologic dz, results in nerve cell death, demyelinating dz of the cns
type IV hypersensitivity reaction: cell mediated
occurs in bouts

Question 2

ms affects male or female

Answer 2

female 2-3x higher

Question 3

race

Answer 3

Caucasian/Scandinavian

Question 4

age

Answer 4

20-40

Question 5

relapsing-remitting

Answer 5

most common, months to yrs, learning disability, visual loss 1 eye, numb/tingling. re-myelination occurs between bouts. oligodendrocytes heal but die over time dt damage is irreversible

Question 6

secondary progressive

Answer 6

Immune attach is constant, attacks last longer happens after relapse remitt, and cont. to get worse, no wax or wane anymore

Question 7

primary progressive

Answer 7

constant attack, progressive disability, pain, HA, Lhermitts sign, paralysis, numbness, diff walking

Question 8

progressive relapsing

Answer 8

normal ms s&s

Question 9

S&S

Answer 9

weak, numb/tingle, unsteady gait, spastic, paraparesis, optic neuritis, sexual dysfunction, tremor, nystagmus, diff speaking , eating,swallowing. worse after hot shower, diff thinking, poor concentration

Question 10

charcots neurologic triad

Answer 10

dysarthria, nystagmus, intentional tremor

Question 11

lhermitte sign

Answer 11

electric shock runs down back and radiates to limb when bending neck forward

Question 12

test

Answer 12

mri is gold standard… sees lesions/plaques, once diag McDonalds criteria is used to evaluate
LP: csf has high levels of antibodies and IgG
visual evoked potential: measures nervous system resp to stimuli

Question 13

tx

Answer 13

relapse-remit: corticosteroids, IV IgG, cyclophosphamide help to decrease freq of relapse,
plasmapheresis removes antibodies
chronic tx: immunosuppressants block t cells from getting into brain
manage other symptoms: depression, PT , cognitive rehab, it D,