MSK Flashcards
(144 cards)
chronic pain at multiple sites - 'pain all over' lethargy cognitive impairment sleep disturbance dizziness headache
fibromyalgia
diagnosis of fibromyalgia
11/18 tender points
management of fibromyalgia
aerobic exercise, CBT
medication = pregabalin, duloxetine and amitriptyline
severe pain
erythema
swelling
usually the 1st MTP joint affected
hx of high purine diet, thiazide use and excessive alcohol/dehydration
gout
investigation for gout
joint aspiration and crystal analysis
negatively birefringent crystals
management for gout
acute = NSAIDs (& appropriate gastroprotection)
colchicine can be given but slower to act
chronic = allopurinol, might start with colchicine
second line = febuxostat
pain mainly in the hip and shoulder pain/aching in the morning stiffness in the proximal limbs polyarthralgia lethargy depression low grade fever
polymyalgia rheumatica
Ix for PMR
ESR/CRP
management of PMR
prednisolone
hot, swollen, episodic attacks of joints
knee, wrist and shoulders mainly affected
pseudogout
investigation of pseudogout
aspiration = positively birefringent crystals
(exclude septic arthritis)
calcium pyrophosphate
management of pseudogout
IA steroid injection
NSAIDs
arthritis uveitis urethritis fever dactylitis
hx of GI/GU infection 1-4 weeks prior
usually male and HLA-B27
reactive arthritis/reiter’s syndrome
management of reactive arthritis/reiter’s syndrome
NSAIDs first line
steroid second line
usually in 20-30s , more common in females
multiple, peripheral joins - MCPs and PIPs
symmterical, joint pain and stiffness
stiffness worse in the morning - improves with as the day goes on
positive squeeze test
rheumatoid arthritis
Diagnosis of rheumatoid arthritis
anti-CCP
X - rays = erosions
management of rheumatoid arthritis
DMARDs - methotrexate/sulfasalazine
- usually taken with folic acid
start with bridging steroids
give steroids IM/PO in acute flares
TNF-a/biologics in inadequate responses
Fever, malaise and arthralgia HTN peripheral motor neuropathy livedo reticularis weight loss
commonly with 40-60yrs old and Hep B infections
polyarteritis nodosa
Ix for polyarteritis nodosa
biopsy = full thickness necrotizing inflammation
raised ESR/CRP
normocytic, normochromic anaemia
management of polyarteritis nodosa
steroids
+/- DMARDs
common in knee and DIPs
usually mono/oligoarthritis - asymmetrical
dactylitis
pitting nails
swelling of associated tendons - enthesis
dry erythematous skin
psoriatic arthritis
Ix of psoriatic arthritis
X-ray hands and feet = pencil in cup deformity
ESR/CRP raised
management for psoriatic arthritis
mild cases = NSAIDs
DMARDs and immunosuppressants - TNFa inhibitors
severe dry eyes and dry mouth fatigue arthralgia Raynauds phenomenon vaginal dryness recurrent parotitis positive schimer's test
Sjogren’s syndrome