MSK Flashcards
(228 cards)
what are the bones of the upper limb and pectoral girdle (proximally to distally)?
Sternum clavicle, scapula,Humerus, ulnar+ radius, carpals( scaphoid, lunate, triquitum, pisiform, trapizum, trapezioid, capitate, hamate), metacapals (1-5) and phalanges (distal, middle and proximal except in the case of the thumb which only have proximal and distal).
what are the joints of the pectoral girdle?
sternoclavicular and acromioclavicular.
what are the functions of the skeleton?
- Movement and mobility;
- Haemopoeisis;
- calcium and fat stores;
- protection and support
what are the different types of bone?
- long
- short
- sesamoid
- pneumatic
- accessory
- flat
- irregular.
Describe bone formation and growth
Bone formation can occur via intramembranous or endochondral ossification.
Intramembranous ossification: occurs via mesenchyme differentiating into osteoblasts which then grow out from a set point laying down bone.
Endochondral: occurs via a hyaline template that undergoes ossifcation. This occurs first with the chondrocytes swelling so that the lacunae become confluent and line up. The chondrocytes undergo apoptosis and then secrete alkaline phosphatase and VEGF. This leads to the developement of the periosteal collar and then the formation of the primary ossification centre. There is a massive influx of haemopoetic cells and osteoblasts and clasts. this leads to a breakdown of the the cartillages extracellular matrix and the laying down of boney matrix. Growth continues at the epiphyseal plates after birth, these are the 2nd centres of ossification.
describe the pathophysiology of osteogenesis imperfecta
This is due to a genetic mutation in the genese coding for type one collagen. There is a mutation that results in a change in the primary sequence of amino acids so a conformational change results. There is a number of different types of varying severity with the most extreme cases being death at child birth and the milder ones being more prone to fracture. Symptoms of include increased risk of fracture, poor muscle tone, blue sclera and hearing loss. Overall height can be also be affected.
describe the pathophysiology of osteoporosis
Caused by excessive activity of osteoclasts due to loss of inhibition or over proliferation of. It presents with a decreased bone density. Most commonly it arises in post menopausal women and in old age although there is a number of other risk factors (ethnicity, gender, diet etc)
describe the pathophysiology of osteomalacia/rickets
Deficiency of vitamin D that leads to softening to the bones. This leads to easy fracture, and over curvature of the spine.
describe the pathophysiology of paget’s disease.
Pagets disease is due to the excessive breakdown and rebuilding of bone that can lead to pain and malformation of bone structure. There is a chaotic structure to the relaid bone that lacks the uniformity of healthy bone.
Describe the process of fracture repair in bone.
First a haematoma forms that then leads to swelling around the site of injury. Phagocytes then enter into the haemotoma digesting it and then this becomes granulation tissue. This is highly vascularised. Peripheral granulation tissue becomes hyaline cartilage. Then ossification occurs (a combination of both types) this leads to the formation of cancellous bone which then undergoes remodelling to form the normal uniform ostoid structures
Describe the classification of joints
fibrous (syndesmoses, sutures, gomphoses), cartilagenous (synchondrosis, symphysis), synovial
Describe the standard components of a synovial joint.
capsule, membrance, fluid, articulating cartilage, articulating bone.
what are the 5 common sites for mets in bone cancers
lung, breast, prostate, kidney, thyroid
what are the terms for bowleddedness and knock knees
genu vargus and genu valgus respectively
what are the common bone surface landmarks?
tuberosity/tubercle, spines, trochanter, epi/condyles, facet, crest, sinus, meatus, fossa, foramen, fissure, notch.
what are the 6 types of synovial joints?
hinge, saddle, plane, pivot, condyloid, ball and socket.
what contributes to joint stability?
ligaments, muscle tone, size of articular surface.
Name the tarsals an any major boney landmarks
Talus, calcaneus, cuboid, navicular, cuneiforms 3, 2, 1
What are common traumatic injuries to the bones of the foot?
Calcaneus fracture- hard impact onto heel from a high fall, typically disrupts the talocalneal joint where the talus articulates with the calcaneus.
Describe the superficial and deep lymph drainage of the lower limb and any common pathological changes and indications of these
Superfically they accompany the great/small saphoneus vein, terminating at the superficial inguinal lymph nodes/ popliteal lymph respectively.
Deep lymph drainage is from the popliteal to the deep inguinal which then joins the lumbar thoracic lymph.
If enlarged could be due to micro sepsis or uterine cancer mets.
Which veins are autografted in heart bypass surgery and why?
The great saphoneous vein due to it being muscular.
How do varicose veins occurs? What can they result in?
Damage to to valves in superfical veins result in veins remaining engorged. They result in blood pooling and stasis which can lead to the formation of thrombus and as a result Pulmonary embolism.
What is a saphoneus cut down?
Finding the great saphoneous by cutting down anterior to the medial malleoulus but there is a risk to the saphoneous nerve.
Describe the anterior deep venous network of the lower limb
Formed from the common illiac proximally. this branches into the internal and external common illiac. Then there is an internal branch of the obturator., below which the great saphoneous vein joins in the femoral triangle to the femoral vein. lateral circumflex gives rise to the perforating branch and descending lateral. This communicates with the genvicular veins of the knee. Then the anterior tibial and the dorsal arch