MSK CORTEXT Flashcards
(127 cards)
You are the orthopaedic registrar in the fracture clinic. An 8 year old girl has been referred from A + E with a fracture to her right clavicle. She did this when she fell from a swing onto her outstretched hand. She’s comfortable in the broad arm sling she has been given and she’s neurovasularly intact in the right arm. She had no preceding symptoms, such as pain, in the shoulder or collar bone prior to the accident. She is fit and well. On examination, there is a mild deformity in the middle 1/3 of the clavicle at the site of the fracture but the skin is intact. So far, there is nothing atypical about this girl’s story or injury. However, when you look at the x-ray, you notice that the bone at the fracture site isn’t completely normal. There is a lucent lesion in the middle 1/3 of the clavicle with a smooth edge where it meets the more normal looking bone. There is mild expansion of the cortex. What do you suspect has caused this pathological fracture?
A simple bone cyst
A simple bone cyst (aka unicameral bone cyst) is a single cavity benign fluid filled cyst in a bone. They are probably a growth defect from the physis and are therefore metaphyseal in long bones (usually in the proximal humerus and femur) although they can occur in the talus or calcaneus. They may be asymptomatic and an incidental finding on xray (usually a child or young adult), however, they can cause weakness leading to pathological fracture. Treatment with curettage and bone grafting with or without stabilization may be required. Pathological fractures caused by a weakness due to a simple bone cyst usually heal with normal treatment for that fracture, so this patient would be treated conservatively as is usual for a clavicle fracture. However, the patient should be seen in clinic until the fracture has definitely healed. After the fracture has healed, the bone will be stronger than before as the bone cyst will have filled with normal bone!
You are the orthopaedic reigistrar in the out-patient clinic. You are referred an 11 year old boy by his GP because he is concerned about a lump which has appeared on the outside of his thigh, just above his knee. The boy and his father tell you it has grown in size and they’re quite concerned. The lump itself is painless although it sometimes catches on the ilio-tibial band on the lateral aspect of his thigh. The boy is well, he doesn’t complain of any other symptoms and doesn’t have any significant past medical history. There is no family history of similar problems. On examination, the boy is slim and you can feel a firm, bony lump on the lateral aspect of the distal femoral metaphysis. The skin and soft tissues overlying the lump are healthy. You do an x-ray and it shows a bony spur originating from the distal femoral metaphysis. The cortex is otherwise normal. What is the diagnosis?
Osteochondroma The commonest benign bone tumour is an osteochondroma which produces a bony outgrowth on the external surface with a cartilaginous cap (which isn’t visible on the x-ray). These do not usually cause any problems but can produce local pain. There is a very small (1%) risk of malignant transformation and any lesion growing in size or producing pain may require excisional biopsy. Multiple osteochondromata can occur as an autosomal dominant hereditary disorder.
A malignant primary bone tumour which tends to occur in abnormal bone (bone infarct, fibrous dysplasia, post irradiation, Paget’s disease), most commonly in adolescents or young adults
Fibrosarcoma
A malignant tumour of endothelial cells in the marrow. Most cases occur between the ages of 10 and 20. It may be associated with fever, raised inflammatory markers and a warm swelling and may be misdiagnosed as osteomyelitis
Ewing’s sarcoma
The most common form of primary bone tumour, producing abnormal bone. Most cases are seen in younger age groups (adolescence and early adulthood) with 60% involving the bones around the knee
Osteosarcoma
What is the name given to the space chondrocytes occupy?
Lacuna
The cell found in cartilage are called chondrocytes (chondroblasts when immature)
Condition X is a qualitative defect of bone with abnormal softening of the bone due to deficient mineralization of osteoid (immature bone) secondary to inadequate amounts of calcium and phosphorus
Osteomalacia (Ricketts is the same disease occurring in children)

A - Haversian canal
B - Cement line
Malignant soft tissue tumours of muscles? Fat? Blood vessels?
Skeletal Muscle = rhabdomyosarcoma
Fat = liposarcoma
Blood vessels = angiosarcoma
Inflammation of the usually present, small fluid filled sac lined by synovium around joints which prevents friction between tendons, bones, muscle and skin. This inflammation commonly occurs after repeatedpressure or trauma and, therefore, may present as a soft tissue swelling.
Bursitis
A cystic swelling which occurs around a synovial joint or tendon sheath, as a result of herniation or out‐pouching of a weak portion of joint capsule or tendon sheath.
Ganglion
A collection of pus which can be formed secondary to a penetrating wound
Abscess
What is the name of the layer of thin connective tissue that surrounds individual muscle fibres, such as shown at ‘B’?

B = endomysium
The sacromere is defined as the region from one [blank] to the next
z-line

Skeletal muscle
(top left = transverse section, peripheral nuclei)
(top right = long fibres + striations)
The radiographic features of which biochemical bone disorder include: bone enlargement, thickened cortices, thickened trabeculae with mixed areas of lysis and sclerosis?
Paget’s disease
“The chief form of bone found at the epiphyses of long bones is ____ bone.”
Trabecular bone

Chrondrocytes (chondroblasts when immature)
A mostly lucent lesion, with a patchy sclerosis, found within the metaphyseal region of long bones
Enchondroma
A bony spur, originating the in metaphyseal regions of long bones, growing away from the epiphysis.
Osteochondroma
A lucent, multi-loculated cyst found within the medulla of many different bones, often with associated cortical expansion.
Aneurysmal bone cyst
Avascular necrosis is a cause of??
Secondary osteoarthritis
Osteochrondromas are always benign?
NO
The commonest benign bone tumour is an osteochondroma which produces a bony outgrowth on the external surface with a cartilaginous cap. These do not usually case any problems but can produce local pain. However, there is a very small (1%) risk of malignant transformation and any lesion growing in size orproducing pain may require excisional biopsy. Multiple osteochondromata can occur as an autosomal dominant hereditary disorder!!!
Multiple osteochondromata can occur as?
autosomal dominant hereditary disorder.





