MSK disorders Flashcards

(52 cards)

1
Q

What are the paediatric MSK disorders?

A
Benign
-
Malignant (severe, progressive, painful, asymmetric)
-Malignancy
-Non accidentale injury
-Infection
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2
Q

How is the paediatric MSK assessed?

A

pGALS
Gait, Arm, Legs, Spine screen
pREMS
detailed regional examination of MSK

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3
Q

What are the variations of normal posture?

A
#Genu varum (bow legs) 1-3 years 
-can be rickets
-Osteogenesis imperfecta
Blount disease
#Genu valgum (knock knees) 2-7 years
-JIA
#Pes Plans (flat feet) 1-2 years
-tarsal fusion
#In-toeing 1-2 years
-Metatarsus varus
-Tibial torsion
-Femoral anteversion
#Out-toeing 6-12 months
-Femoral retroversion
-Marfan
-Ehler Danlos
#Toe walking 1-3 years
-spastic diplegia
-tight Achilles tendon
-JIA
-Duchenne muscular dystrophy
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4
Q

What are the causes of abnormal posture?

MSK, Neuro

A
#Talipes equinovarus (clubfoot)
-could be positional talipes (normal and passive correctable)
#Vartical talus
#Talipes calcaneovalgus
-dorsiflexed everted foot
-associated with DDH
#Pes planus (Flat feet)
#Tarsal coalition
#Pes cavus
-associated with Friedrich ataxia
#Developmental dysplasia of the hip
#Scoliosis
#Troticollis
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5
Q

What are the features of talipes equinovarus?

A

Foot inverted and supinated
Forefoot adducted
Heel internally rotated and plantation flexed
Shorter foot
Thinner calf muscles
Often bilateral
Fixed in position, can’t fully recorrect passively

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6
Q

What are the causes of CTEV?

A
1:1000 live births, M>F 2:1
Familial or idiopathic
Secondary to oligohydramnios
Malformation syndrome
Spina bifida
Associated with DDH
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7
Q

How is CTEV treated?

A

Promptly with plaster casting (Ponsetti method)

Surgery last line

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8
Q

What are the causes of torticollis?

A
#Congenital
-Sternomastoid tumor (mobile non tender nodule)
resolves in 2-6 months
#Acquired
-Spasm
-ENT infection
-Spinal tumor
-C-spine defects
-Posterior fossa tumor
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9
Q

What is scoliosis?

A

A lateral curvature in the frontal plant of the spine

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10
Q

What are the causes of scoliosis?

A
#Idiopathic (most common, mostly late onset, mostly pubertal girls)
#Congenital
-Hemivertebra
-Spina bifida syndromes (VACTERL)
#Secondary
-CP
-Muscular dystrophy
-NF
-Marfan
-LLD from JIA
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11
Q

What is Developmental dysplasia of the hip?

A
Spectrum of disorders
From dysplasia to subluxation to frank dislocation of the hip
If missed, will lead to hip dysplasia
1:1000 live births
Mostly resolves spontaneously
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12
Q

How is DDH screened in newborns?

A

Barlow test to check if posteriorly dislocating
Ortolani test to relocate by abducting
Repeat tests at 2 months
Presents later as a limp or abnormal gait

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13
Q

What are the genetic MSK conditions?

A
#Achondroplasia
-AD
-50% new mutations
#Cleidocranial dysostosis
-AD
#Marfan syndrome
-AD
#OI type I
-AD
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14
Q

What are the features of Marfan syndrome?

A
Tall stature
Arachnodactyly
Hyperextensible joints
High arched palate
Lens subluxation
Myopia
Lower segment>upper segment
Arm span> height
Scoliosis
AR, MVP, MR, Aortic aneurysms
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15
Q

What is osteogenesis imperfecta?

A
Group of disorders of collagen metabolism
Causing bone fragility, bowing, pathological fractures
Type I most common (AD)
-Childhood fractures
-Blue sclera
-Deafness
Rx Bisphosphonates
Type II is lethal.
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16
Q

What are the causes of arthritis in children?

A
Reactive arthritis
Septic arthritis
JIA
Henoch-Schonlein purpura
Systemic lupus erythematosus
Juvenile dermatomyositis
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17
Q

What are the causes of painful limbs?

A
Growing pains
Hypermobility
Complex regional pain syndromes
Osteomyelitis
Malignancy
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18
Q

How to diagnose growing pains?

A
3-12 years
Pain is symmetrical and not limited to isolated areas
Pain not present on waking
No limp or disability
Otherwise healthy
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19
Q

What are the causes of hyper mobility?

A

Normal
Marfan
Down
Ehlers-Danlos

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20
Q

What are the red flags in a child with back pain?

A
Young age
High fever
Waking up in the night with persistent pain
Painful scoliosis
Focal neurology (incontinence)
Loss of weight, anorexia
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21
Q

What are the causes of back pain in a child?

A
#Mechanical
#Tumors (osteoid osteoma)
#Osteomyelitis/discitis of vertebra
#Nerve root compression
#Spondylolysis/spondylolisthesis
#CRPS
22
Q

What are the causes of acute onset limb pain in children?

A
#Accidental injury
#Non aciidental injury
#Osteomyelitis
#Malignancies
-ALL
-Neuroblastoma with mets/arthritis
-Osteogenic sarcoma
-Ewing tumor
#Benign tumor
-Osteoid osteoma
23
Q

What is osteomyelitis?

A

Infection of the metaphysic of long bones
Commonly the distal femur and proximal tibia
But any bone can be affected
Usually from hematogenous spread
Can be from direct spread or inoculation

24
Q

What are the causative organisms in osteomyelitis?

A
S aureus
Strep
H influenzae
Salmonella (in Sickle cell anemia)
TB
25
What are the complications of osteomyelitis?
``` Chronic osteomyelitis with sinus discharge Bone necrosis Limb deformity Amyloidosis Joint destruction Septic arthritis Subperiosteal abscess Sepsis ```
26
How is osteomyelitis managed?
Blood cultures and FBC with CRP and Xray/USS IV Abx until CRP drops and clinical recovery Continue PO Abx for several weeks Aspirate if very grave Surgical drainage if no response Splint the limb and mobilise later
27
What are the causes of a painful knee?
Referred from hip Local knee -Osteochondritis of patellar tendon insertion -Chondromalacia of patellar articular cartilage -Avascular necrosis of femoral condyles -Patella subluxation and dislocation
28
What are the causes of acute painful limp?
``` #1-3 years -Septic arthritis/osteomyelitis -Transient synovitis -Trauma -ALL/Neuroblastoma #3-10 years -Transient synovitis -Septic arthritis/osteomyelitis -Trauma/overuse -Acute Perthes disease -JIA -ALL -CRPS #11-16 years -Mechanical -Acute slipped capital femoral epiphysis -AVN of femoral head -Reactive arthritis -JIA -Septic arthritis/osteomyelitis -AVN of femoral condyles -Bone tutors/malignancy CRPS ```
29
What are the causes of chronic intermittent limp?
``` #1-3 years DDH CTEV CP JIA #3-10 years Chronic Perthes disease DMD JIA Tarsal coalition #11-16 years Chronic slipped capital femoral epiphysis JIA Tarsal coalition ```
30
What are the clinical features of transient synovitis of the hip?
Onset - acute limp, non weight bearing, follows viral infection Fever - mild/absent Appearance - Clinically well, 2-12 year olds Hip movement - Painful on moving, limited internal rotation, no pain at rest WBC - normal CRP/ESR - normal, slightly high USS - effusion Xray - normal Management - rest, analgesia Follow up - resolves within a week 3% may get Perthes' disease
31
What are the clinical features of septic arthritis?
Onset - acute limp, non weight bearing Fever - high Appearance - Clinically ill looking Hip movement - held in flexion, pain at rest, worsens on moving WBC - high CRP/ESR - high USS - effusion Xray - widened joint space Management - aspiration, antibiotics, rest, analgesia, blood cultures Follow up - joint destruction if untreated
32
What is the most common cause of acute hip pain in children?
Transient synovitis
33
What is Perthes' disease?
Avascular necrosis of the capital femoral epiphysis of the femoral head due to interruption of blood supply Followed by revascularisation and reossification over 18-36 months M>F 5:1 20% bilateral Insidious limp, hip or knee pain Xray both hips, can do MRI, bone scan Prognosis good if <6 years and <50% epiphysis affected Complications - femoral head deformity, degenerative arthritis
34
How is Perthes' disease managed?
Early (hyper dense femoral head) -bed rest and traction Late (fragmented irregular femoral head) -maintain hip in abduction
35
What is slipped capital femoral epiphysis (SCFE)?
Displacement of the epiphysis of the femoral head postero-inferiorly which can lead to avascular necrosis Restricted abduction and internal rotation 10-15 years of age Mostly in obese boys 20% bilateral Associated with hypothyroidism, hypogonadism Mx = pin fixation in situ
36
What are the causes of polyarthritis?
Infection - bacterial, TB, viral, atypical, reactive, RF IBD - CD, UC Vasculitis - HSP, Kawasaki disease Haematological - Hemophilia, SCD Malignancy - ALL, neuroblastoma CTD - JIA, SLE, dermatomyositis, MCTD, PAN Genetic - cystic fibrosis
37
What are the viruses causing polyarthritis?
``` Rubella Mumps Adenovirus Coxsackie B Herpes Hepatitis Parvovirus ```
38
What is the most common form of arthritis in children?
Reactive arthritis (GI infection, strep infection, RF) Transient joint swelling < 6 weeks Ankles or knees, low grade fever NSAIDs only Salmonella, Shigella, Capylobacter, Yersinia Chlamydia, Gonococcus, Mycoplasma, Borrelia
39
What are the features of septic arthritis?
``` Most common in <2 years old Acutely unwell child with a joint with acute inflammation Can cause bone destruction Staph aureus (single joint), Hib (multiple joints) Pseudoparesis with hip in flexion, abduction and external rotation ```
40
What are the features of SLE in children?
Young pubertal girls Malaise, arthralgia, malar rash Kidney, CNS, lung involvement
41
What are the features of juvenile dermatomyositis?
JDMS is rare Malaise, proximal myopathy Facial malar rash over nasal bridge Heliotrope rash of eyelids
42
What are the features of HSP?
``` Most common vasculitis of children Purpuric rash over lower legs and buttocks Ankle or knee arthritis Abdominal pain Hematuria Proteinuria ```
43
How is septic arthritis investigated and managed?
``` FBC, CRP, BCx, Aspiration and USS Bone scan and MRI IV Abx, joint drainage Immobilize then mobilise Analgesia ```
44
What is Juvenile Idiopathic Arthritis?
Most common chronic inflammatory joint disease in children Persistent joint swelling > 6 weeks Before 16 years of age In the absence of infection or other causes 95% of cases are different from Rheumatoid arthritis Affects 1:1000 7 subtypes based of number of affected joints in the first 6 months of the disease
45
What are the subtypes of JIA?
Polyarthritis (>4 joints) - poor prognosis Oligoarthritis (4 or less joints) - most common, best prognosis Systemic (with fever and salmon pink rash) - poor prognosis Psoriatic Enthesitis Undifferentiated
46
What are the clinical features of JIA?
Gelling (stiffness after rest) Morning stiffness Pain Intermittent limp Behavioural change and avoidance behaviour Joint swelling (fluid, inflammation, proliferation) Bone overgrowth (deformities)
47
What are the complications of JIA?
``` Chronic anterior uveitis and blindness Flexion contractures in joints Growth failure Anemia of chronic disease Delayed puberty Osteoporosis Amyloidosis and proteinuria with CKD ```
48
How is osteoporosis managed?
Calcium and vit D supplements Regular weight bearing exercises Minimise corticosteroid therapy Bisphosphonates
49
How is JIA managed?
``` Goals are to induce remission and prevent deformity and disability Refer to Paed Rheumatology Education and support for child and family Physiotherapy to protect joint function Eye referral Avoid contact sports in active flares NSAIDs during flares IA steroid injections Weekly SC MTX with FBC, LFT monitoring IV Methylprednisolone pulses Biologics in severe cases Joint Xrays ANA and RF and HLAB27 ```
50
What is the prognosis of JIA?
``` 1:3 will have active disease as adults Joint replacement surgery Vision loss Fractures from osteoporosis Psychosocial effects ```
51
What are the features of Systemic JIA?
``` Fever, salmon pink macular rash LN and HSM Serositis Oligo or poly arthritis Poor prognosis 1:1 male female ```
52
What are the features of polyarthritis JIA?
``` Either RF + or - Females 5 times more likely Symmetrical large and small joints and fingers Rheumatoid nodules in RF + C spine and TMJ joints in RF - ```