MSRA: Overdose + Antidotes Flashcards

1
Q

Paracetamol

A

1hr - Activated charcoal
NAC

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2
Q

Carbon Monoxide

A

100% Oxygen

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3
Q

Salicylates (Aspirin)

A

Urinary alkalinisation with IV bicarb

Haemodialysis

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4
Q

Opioids

A

Naloxone

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5
Q

Digoxin

A

Digoxin specific antibody

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6
Q

Benzodiazepines

A

Flumazenil

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7
Q

Cyanide

A

Hydroxycobalamime

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8
Q

Tricyclic Antidepressants

A

IV Bicarbonate

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9
Q

Lithium

A

Haemodialysis

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10
Q

Warfarin

A

Vitamin K

Prothrombin

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11
Q

Heparin (UF)

A

Protamine sulphate

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12
Q

B-blockers

A

Atropine, then Glucagon

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13
Q

Organophoshates

A

Atropine

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14
Q

Anti-freeze (ethylene glycol)

A

Fomepizole

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15
Q

Methanol

A

Fomepizole/Ethanol

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16
Q

Iron

A

Desferrioxamine

17
Q

Lead

A

Dimercaprol/Calcium Edetate

18
Q

What are the indications for starting NAC?

A

Staggered overdose (taken over more than 1 hour)
Serum levels above treatment line at 4 hours
Presents between 8-24 hours and taken more than 150mg/kg

19
Q

What are the features of carbon monoxide poisioning?

A

Headache **
Nausea, vomiting
Vertigo
In severe cases: Deep flushed cherry red skin, hyperpyrexia

20
Q

What are the symptoms in TCA overdose?

A

Tachycardia
Sweating
Reduced GCS

21
Q

What are the ECG changes in TCA overdose?

A

Sinus tachycardia
Widened QRS
Prolonged QT