MTAP FINALS Flashcards

(65 cards)

1
Q

It’s used for detection of specific infectious agent

A

Immunology and Serology

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2
Q

Defective immune response/system

A

Autoimmune disorder

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3
Q

Pertains to the variable region of the antibody

A

Idiotype

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4
Q

Lyse on the heavy chain structure immunoglobulins

A

Isotype

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5
Q

Sequence in the constant region

A

Allotype

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6
Q

It has 2 different chain

A

Light Chain

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7
Q

It has 22 chromosome

A

Lambda

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8
Q

Found between CH1 and CH2

A

Hinge Region

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9
Q

MHC means

A

Major Histocompatibility Complex

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10
Q

Dictated by several factors. Where antibody producing capability of the antigen when it is present .

A

Immunogenicity

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11
Q

It considered as a rich source of antigen

A

Graft Types

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12
Q

Self antigen that belongs to the host.

A

Autoantigen

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13
Q

Derived from individual’s body/ patient’s own body

A

Autograft

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14
Q

It’s responsible for the molecular weight of antigen

A

Carrier portion

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15
Q

Stable, the best and strongest antigen

A

Protein

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16
Q

Most common carrier is Albumin

A

Hapten

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17
Q

It can induce an immune response

A

Immunogen

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18
Q

It enhance the immune response; to have a greater immune reactivity

A

Adjuvants

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19
Q

Induces the hypersensitivity reactions

A

Allergen

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20
Q

The immune response is exaggerated that can be harmful to individual

A

Hypersensitivity

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21
Q

It must be recognized as foreign or non-self to induce immune response

A

Foreigness

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22
Q

It’s exist in unrelated plants/animals; either identical/closely related in structure

A

Heterophile antigen

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23
Q

It’s the most fatal (ex. Anaphylaxis/ Severe Asthma)

A

Type I Hypersensitivity Reaction

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24
Q

It’s the surface of antigens; ABO, Rh antigens

A

Glycoproteins

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25
Least immunogenic; easily disintegrate in the circulation -> shorter circulation life
Nucleic Acids, Lipids and Amino Acids
26
It has constant amino acid sequence (constant region) allotype
Carboxyterminal
27
Capable of antigen binding even without the Fe but cannot agglutinate
Two fab fragments
28
Responsible for the specific antibody
Variable region
29
Fragment is crystalline; involved in the Ig biologic function
One Fc fragment
30
Heavy chains are interconnected
Disulfide linkages
31
With varying antibody specificity (variable region) Allotype
Aminoterminal
32
Both light and heavy chains are hold together by:
Covalent disulfide bonds
33
It's also known as Immunoglobulins
Antibodies
34
It's responsible for cytotropic reaction involving WBC
CH3
35
It's connect with receptors in cell membrane
CH3,
36
Binds with complement protein specifically C1Q
CH2
37
Found between the CH1 and CH2; flexibility of the antibody
Hinge region
38
Responsible for the light chain; either kappa or lambda
CL
39
It enhances the phagocytosis by facilitating the linking/ cross bridging of the phagocytes and the data target antigens
Opsonin
40
Only antibody with secretory component
IgA
41
The control of antibody secretion/release in the circulation
Immunoregulation
42
Only Ig that has specific receptor on mast cells
IgE
43
It has a 21 to 23 days of life
IgG
44
What is the molecular weight of IgM
900T
45
It has 5 Domains
IgM and IgE
46
It's responsible for mucosal immunity
IgA
47
It's predominant antibody in primary immune response
IgM
48
Their immune system is already weak
Geriatric patients
49
An antibody titer that is increasing the logarithmically
Log
50
Antibody titer degraded
Decline
51
It occurs in four phases after exposure to an antigen
Primary response
52
No antibody is detectable
Lag
53
Antibody titer is stabilizes
Plateau
54
Other name of secondary response
Anamnestic/memory response
55
It helps the immune cells to determine self from nonself
Generic control of immune response
56
Their immune system is different from adults and children
Neonatal
57
It's predominant Ig in secretions
Secretory Ig
58
It binds the basophil and mast cells
Reagenic Ig
59
It has 2-3 days of life
IgD and IgE
60
Best agglutinating antibody
Fxn's
61
Antibody is transferred from mother to developing baby
Acquired natural passive immunity
62
It's damaging and harmful to the baby
HDFN
63
It will not precipitate /agglutinate the antigens but can only bind the epitope of the antigens
Monovalent type
64
It produces by B lymphocytes or plasma cells in response to antigen stimulation
Antibodies
65
GOOD LUCK!!!♥️