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MTB 2 Flashcards

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1
Q

Most appropriate next step in pt w influenza and w/in 48 hrs

A

Nasopharyngeal swab or wash - Ag detection

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2
Q

Who should get annual influenza vaccine

A

> 50
Health care workers
Preg - 2nd/3rd
Annual

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3
Q

Most common causes of bloody diarrhea

A

Salmonella

Campylobacter

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4
Q

Presentation of E.coli 0157

A

HUS
Hemolysis
Increased Cr
Low platelets

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5
Q

Bloody diarrhea + Hx of liver dz

A

Vibrio vulnificus

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6
Q

Bloody diarrhea + hemochromatosis or blood trasfusions

A

Yersinia - high affinity for Iron

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7
Q

Best initial test in bloody diarrhea

A

Blood and/or fecal leukocytes

Lactoferrin = better choice

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8
Q

Most accurate test in bloody diarrhea

A

Stool culture

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9
Q

DDX for diarrhea w no blood or WBCs in stool

A
  1. Viral
  2. Giardia
  3. Cryptosporidiosis
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10
Q

Preformed toxins ass’d with vomiting

A

Bacillus

Staph

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11
Q

Scrombid Infxn

A

Rapid onset
Flushing, wheezing, rash
Fish - decayed
Tx: Antihistamines

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12
Q

TX for infectious diarrhea

A

Mild: Oral fluids
Severe: fluids + Cipro

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13
Q

Labs elevated in hepatitis

A

Direct BR
AP
ALT:AST

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14
Q

High PT in hepatitis

A

Risk for Fulminant hepatic failure

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15
Q

Best initial test hepatitis

A

IgM Ab for acute infxn

IgG Ab for resolution

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16
Q

Test for dz activity in HCV

A

PCR for RNA level

= viral replication

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17
Q

Serologic findings Acute or Chronic HBV Infxn

A

HBsAg +
HBeAg +
HBcAb IgM or IgG +
HBsAb -

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18
Q

Serologic finding Resolved/old Infxn HBV

A

HBsAg -
HBeAg -
HBcAb IgG +
HBsAb +

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19
Q

Serologic finding Vaccination HBV

A

HBsAg -
HBeAg -
HBcAb IgG -
HBsAb +

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20
Q

Serologic finding Window Period

A

HBsAg -
HBeAg -
HBcAb IgM + THen HBcAb IgG +
HBsAb -

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21
Q

What does HBsAg measure

Study These Flashcards
A

Active Viral Particles

22
Q

Which HBV marker correlates w the amt or quantity of active viral replication

Study These Flashcards
A

HBeAg

E antigen is correlated to DNA Polymerase

23
Q

Which HBV marker indicates that active infxn has resolved and is no longer transmissable

Study These Flashcards
A

HBsAg - as long as present, still some viral replication occurring
Transmissability ceases when DNA polymerase ceases

24
Q

Which HBV marker is the best indication for need for tx w antiviral meds?

Study These Flashcards
A

HBeAg = strongest indicator of active viral replication

25
Which HBV marker is best indicator that pregnant woman will transmit infxn to her child
HBeAg
26
AEs of IFN
``` Arthralgia/myalgia Leukopenia Thrombocytopenia Depression Flu-like Sx's ```
27
What is the goal of chronic hepatitis therapy
1. Reduce DNA Polymerase to undetectable levels | 2. Convert pts w e-Antigen to e-Antibodies
28
Tx for HBV
Tenofovir - blocks DNA polymerase the most Enteavir Adefovir
29
When are Hep C pts treated and with what | Goal?
If PCR-RNA is elevated IFN and Ribavarin Goal = undetedtable viral load
30
AE of Ribavarin
Anemia
31
Best initial test for urethritis
Urethral swab for Gram stain
32
WU for urethritis
1. Swab 2. Culture 3. Treat
33
Most accurate test for urethritis
Urethral culture DNA Probe Nucleic acid amplification test
34
TX for urethritis
Ceftriaxone/cefixime + Azithromycin/Doxycycline
35
Presentation of Urethritis
Dysuria Urinary Frequency Burning
36
Presentation of Cervicitis
Cervical Discharge | Inflamed strawberry cervix
37
Most accurate test for PID
Laparoscopy
38
PID TX Inpatient
Cefoxitin/Cefotetan + Doxycycline
39
PID TX Outpatient
Ceftriaxone | Doxycycline
40
PID TX pts w anaphylaxis with PCN
Outpatient - Levofloxacin + Metronidazole | Inpatient - Clindamycin + Gentamicin
41
Presentation of herpetic whitlow | TX
Viral Infxn of hand Throbbing pain -> swollen, soft, tender Self limiting Health care workers
42
Ulcerative genital dz with: | Painless ulcer, painless nodes
Syphilis
43
Ulcerative genital dz with: | Painful ulcer
Chancroid - H. ducreyi
44
Ulcerative genital dz with: | LNs tender and suppurating
Lymphogranuloma venereum
45
Ulcerative genital dz with: | Vesicles prior to ulcer and Painful
HSV
46
Dx test for syphilis
Dark field microscopy VDRL or RPR FTA or MHA-TP to confirm
47
DX test for Chancroid
Stain/culture specialized media
48
DX test for Lymphogranuloma venereum
Complement fixation titers in blood | Nucleic acid amplification
49
Most accurate test for HSV
Viral culture
50
Syphilis TX
Pen G | Doxycycline if allergic
51
TX for chancroid
Azithromycin
52
TX for lymphogranuloma venerum
Doxycycline

Infectious (4 decks)

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