Flashcards in Multiple Choice from Exams 1-4 Deck (21):
How does the dielectric constant after the electrostatic energy
Which of the following is true of a buffer with a pKa of 8.0
at pH 6, the buffer would be completely protonated
Relies on the chance charge separation of one atom to induce a dipole in a second atom
Van der Waals interactions
Which amino acids have a side chain that is negatively charged at physiological pH
aspartate and glutamate
Essential amino acids
Which of the following is true of the peptide bond in naturally-occurring proteins
It has partial double bond characteristics
Which of the following is true of protein structure
all proteins have tertiary structure
What is true of a Ramachandran plot?
a. Secondary structure types have characteristics locations on a Ramachandran plot
b. Some locations on a Ramachandran diagram are not permitted for amino acids because of steric hindrance
c. It shows the combinations of torsion angle within a protein structure
What is true of protein folding?
a. it is a random series of events that spontaneously results in the correct fold
b. the folded state of the protein is the lowest energy state
c. correct intermediate forms are progressively stabilized until the completely correct fold is reached
A mutation in which protein results in the disorder epidermolysis bulls simplex (EBS)
Which of the following trends is/are observed during protein purification
the specific activity increases with each purification step
Nitrogenase transfers electrons from ferredoxin to N2 to make ammonia. What class of enzyme is this?
Hexokinase has a Km of 0.9 mM for its substrate glucose. Glucokinase has a Km of 90 mM for glucose. Which enzyme has the highest affinity for glucose?
shift the T/R equilibrium for both allosteric models
The influence of the substrate on allosteric enzymes to alter their T/R equilibrium
What is the molecular basis of gout?
Urate accumulates in the fluid and lining of joints causing inflammation. PRS catalysis at the active site is unchanged. PRS enzyme loses its feedback-inhibition response to purines
Glyphosphate binds to the enzyme EPSP at the active site instead of the substrate molecule PEP and prevents catalysis. What type of inhibitor is it?
Which of the following is true of the allosteric effectors of hemoglobin
a high concentration of H+ facilitates O2 release
Which of the following best describes the molecular basis of ion channel selectivity?
Ion channels only allow one specific ion through their selectivity filter.
Which of the following is true of biological membranes
membranes are highly impermeable to charged molecules