Multiple Choice Questions Flashcards

(62 cards)

1
Q

Side effects of quinidine in the horse

A

Colic
Laminitis
Tachycardia
Can cause tdp in general

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2
Q

Most common clinical sign in cow with AF

A

GI disease

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3
Q

PDE 3 mech

A

Increase cAMP

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4
Q

PDE5 mech

A

Increase cGMP

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5
Q

What is an Austin flint murmur

A

AI causing flutter of the mitral valve - middiastolic or presystolic

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6
Q

Quest study- what does not have neg hazards ratio?

A
Associated with longer survival:
Pimobendan
Ckcs
Low furosemide
Lower vhs
Lower la/ao
Lower lvid
Higher creatinine
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7
Q

Side effect of spironolactone cats

A

Facial pruritis

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8
Q

What increases digoxin levels

A

Hypokalemia
Azotemia

Other choices were:
Amiodarone
Hypercalcemia

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9
Q

Effect of hyperkalemia on cell

A

Hypopolarized membrane

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10
Q

What cause low O2 saturation?

A

Options included
Exercise
Hypoxia
Polycythemia

Hypoxia?

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11
Q

What does the c wave coordinate with?

A

Closure of av valves

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12
Q

What arrhythmia to give unsynchronized cardioversion for?

A

VF?

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13
Q

What species are right coronary dominant?

A

Humans
Pigs
Horses

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14
Q

What species are left coronary dominant?

A

Dog
Cat
Ruminant

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15
Q

Most common bypass tract in dog

A

Right posteroseptal
Retrograde
Unidirectional

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16
Q

B1>a>B2

A

Norepinephrine

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17
Q

B1>B2>a

A

Dobutamine

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18
Q

B1=B2>a

A

Epinephrine

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19
Q

Most common heart disease in ferrets

A

Aortic regurgitation >MR

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20
Q

Most common cardiomyopathy in ferrets

A

DCM

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21
Q

Surgery of choose for ToF

A

Modified blalock taussig

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22
Q

What is modified blalock taussig

A

Graft to connect L subclavian to aorta or pa

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23
Q

What is blalock taussig

A

L subclavian to PA by anastomosing vessels

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24
Q

What is Potts

A

Anastomoses btwn PA and desending AO

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25
What is waterson
Anastomoses btwn rPA and ascending ao
26
Most common valve regurg in horses
AI
27
Best ACEi in horses
Benazepril
28
Best treatment for GS inherited arrhythmias
Mexiletine and sotalol together
29
Most common iguana heart prob
Valve regurg and mineralization of great vessels
30
Case of smoke in LA
Plasma protein interactions
31
Embryologist origin of CTS
Stenotic connection of pulmonary veins to LA
32
Embryonic origin of CTD
Persistence of the right sinus valve
33
Which beta blocker metabolized in the liver?
Propranolol>metoprolol
34
Which beta blocker crosses bbb
Propranolol
35
Chem changes with hyperaldosteronism
Low renin Low K High renal K excretion
36
Protect study- survival times
Median time to CHF/SCD 9 months longer in dobies with pimo
37
Quest
Better hr | Low creatinine
38
Cause of inherited arrhythmias in gsd
Abnormal serca | Predisposed to eads and dads
39
Mech of ventriculophasic SA
1. Storm of baroreceptors from increased arterial pressure causes increased vagal tone. 2. Increased blood flow to sinus node diffuses metabolites and slows next discharge. 3. Inhibition of bainbridge reflex
40
Concealed conduction
Incomplete cardiac impulse conduction through specialized conduction tissue. This shows effects on next p-QRS-t, and may lead to conduction delay, Avb, conduction enhancement, etc.
41
How does a VVI pacemaker set at 90 bpm with a refractory period of 320 ms respond to a premature ventricular complex occurring at 250 ms after the last paced beat?
It would be sensed in the refractory period but would not reset timing cycles.
42
What is noise reversion?
Inappropriate asynchronous pacing. The pacemaker is switched to a synchronous pacing with repetitive refractory sensing. This is to protect against noise being mistaken for cardiac events with the consequence of inhibition of pacing
43
Two ways to fix noise reversion
One. Shorten refractory. | Two. Decrease the sensitivity.
44
Why does Treppe effect go away with Heart failure
Decreased serca with heart failure, means decreased ca uptake
45
When is renin released?
Hypovolemia Hyponatremia Diuretics Circulating catecholamines
46
Best treatment for WPW
Procainamide
47
4 causes of acquired pulmonary artery stenosis
Chronic ps developing into peripheral PS 2. Neoplasia 3. Ligation of PA during PDA ligation 4. Hematoma
48
What enzyme causes cardiac cachexia
Angiotensin 2 and aldosterone
49
What causes inotropic effects
Forskolin
50
What is branhams sign?
Decrease in heart rate with increase in diastolic BP, as seen during pda ligation.
51
List 10 Minor criteria for endocarditis
Fever Medium to large breed dog Subaortic stenosis Vascular phenomena such as arterial emboli Immuno logical phenomenon such as polyarthritis Bartonella serology greater than one to 1024 Positive blood cultures not meeting major criteria New or worse heart murmur Chronic catheter Immunocompromise Predisposing heart conditions Repeated non-sterile drug in ministration Echo consistent with IE
52
3 endothelin-1 functions
Vasoconstriction Increased collagen synthesis Sm muscle proliferation Vascular remodeling
53
3 endothelium antagonists for pht
Bosentan Ambrisentan Macitentan
54
Prostacyclin functions
Vasodilation | Inhibits sm muscle proliferation
55
3 prostacyclin analogs
Iloprost Beraprost Epoprostenol
56
PDE5 inhibitors
Sildenafil | Taladafil
57
Serotonin affects what cell type in valve?
VIC to myofibroblast
58
What high serotonin syndrome looks similar to DMVD?
Carcinoid syndrome, but this affects tricuspid more than mitral
59
What cell type decreases with DMVD?
VEC
60
What happens to atrialis layer with DMVD?
Increased ECM
61
What happens to fibrosa?
Disorganized collagen
62
What happens to spongiosa?
Most affected layer- disorganized and more gags/proteoglycans.