Multiple endocrine neoplasia

Question 1

What is MEN?

Answer 1

multiple endocrine neoplasia

Question 2

What is the mode of inheritance of MEN?

Answer 2

AD

Question 3

How many types of MEN are there?

Answer 3

MEN type 1
MEN type 2a
MEN type 2b

Question 4

Which conditions are associated with MEN type 1?

Answer 4

parathyroid hyperplasia
pancreatic islet cell tumour
pituitary tumours

Question 5

Which conditions are associated with MEN type 2a?

Answer 5

medullary thyroid carcinoma
pharochromocytoma
parathyroid hyperplasia

Question 6

Which conditions are associated with MEN type 2b?

Answer 6

medullary thyroid carcinoma
phaeochromocytoma
mucosal neuromas

Question 7

Which MEN is associated with phaeochromocytomas?

Answer 7

type 2a and 2b

Question 8

What is the 10% rule of the pattern of MEN tumours?

Answer 8

10% bilateral
10% cancerous
10% outside the adrenal gland

Question 9

Name two aspects of diagnosing phaeochromocytoma

Answer 9

24 hr catecholamines

Plasma free metanephrines= breakdown product of adrenaline

Question 10

Name three features of phaechromocytoma presentation

Answer 10

anxiety
sweating
headache
hypertension
tremor
palpitations
tachy

Question 11

Three management options for phaeochromocytoma?

Answer 11

alpha blockers
beta blockers
adrenalectomy