Muscle Flashcards

(51 cards)

1
Q

cilia and flagella are outgrowths of

A

cell membrane

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2
Q

flagellar movement helps in

A

swimming of spermatozoa
maintenance of water current in canal system of sponges
locomotion of protozoans like Euglena

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3
Q

embryonical origin of muscle

A

mesoderm

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4
Q

how much percent of our body weight is muscles

A

40-50

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5
Q

special properties of muscles

A

excitability
contractility
extensibility
elasticity

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6
Q

three types of muscles

A

skeletal
smooth / visceral
cardiac

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7
Q

a skeletal muscle is made up of bundles of

A

fascicles

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8
Q

fascicles are held together by

A

fascia (collagenous connective tissue)

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9
Q

plasma membrane of a muscle fibre

A

sarcolemma

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10
Q

cytoplasm of muscle fibre

A

sarcoplasm

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11
Q

sarcoplasm contains many nuclei
hence, state of muscle fibre

A

syncytium

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12
Q

endoplasmic reticulum of muscle fibre

A

sarcoplasmic reticulum

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13
Q

sarcoplasmic reticulum is the store hous of which ions

A

calcium

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14
Q

band that contains actin

A

I band (isotropic)

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15
Q

band that contains myosin

A

A band (anisotropic)

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16
Q

thick filament

A

myosin

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17
Q

thin filament

A

actin

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18
Q

elastic fibre which bisects the I band

A

Z line

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19
Q

fibrous membrane which bisects the A band

A

M line

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20
Q

portion of myofibril between two successive Z lines

A

sarcomere

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21
Q

in resting state, non overlapping zone is of thick filaments is called

22
Q

each ____ actin is a polymer of monomeric ____ actins

A

F (filamentous)
G (globular)

23
Q

two filaments of another protein _______________ run close to F actins throughout its length

24
Q

a complex protein ___________ is distributed at regular intervals on tropomyosin

25
in resting state, a subunit of troponin masks __________________________ on actin filament
myosin binding site
26
monomer of myosin is called
meromyosin
27
parts of a meromyosin
globular head with a short arm tail
28
globular head and short arm are called
heavy meromyosin (HMM)
29
tail is called
light meromyosin (LMM)
30
heavy meromyosin has binding sites for ____________ and ____________ therefore, it is called ___________ enzyme
actin atp atpase
31
mechanism of muscle contraction is best explained by which theory
sliding filament
32
what does sliding filament theory state
that contraction of a muscle fibre takes place by sliding of the thin filaments over the thick filaments
33
muscle contraction is initiated by a signal sent by _______ via _________
CNS motor neuron
34
a motor neuron along with muscle fibres connected to it constitute
motor unit
35
junction between a motor neuron and sarcolemma of muscle fibre
neuromuscular junction / motor-end plate
36
a neural signal reaching the neuromuscular junction releases ________________________ which generates ________________________ in sarcolemma
neurotransmitter - acetyl choline action potential
37
action potential spreads through the muscle fibre and causes
release of calcium ions in the sarcoplasm
38
increase in calcium ion levels leads to
binding of calcium ion with a subunit of troponin and thereby remove masking of myosin binding site
39
utilising energy from ___________________, myosin head now binds to exposed sites on action to form _______________
atp hydrolysis cross bridge
40
during contraction of sarcomere, _______ retains the length and _____________ gets reduced
A band I band
41
myosin, releasing ____________ goes back to relaxed state
adp and ip
42
how is cross bridge broken
a new atp binds to myosin
43
till when does this cycle continue
till calcium ions are pumped back to the sarcoplasmic reticulum which results in the masking of actin filaments
44
repeated activation of muscles can lead to accumulation of ______________ due to anaerobic breakdown of glycogen, causing ___________
lactic acid fatigue
45
red coloured oxygen storing pigment
myoglobin
46
reddish appearance in some muscles is due to
high content of myoglobin
47
reddish muscles are called
red muscle fibres
48
amount of mitochondria in red muscles and why
high amount to form more atp using stored oxygen aerobically
49
why do some muscles appear pale or whitish
less content of myoglobin
50
amount of mitochondria in white muscles and why
less amount depend on anaerobic processes for energy
51
amount of sarcoplasmic reticulum in white fibres
high