Muscle Flashcards
(29 cards)
3 Main Molecular Motors in Euk Cells
Kinesin, dynein, and mysoin
Why did muscle cells first evolve
To move things around inside single-celled organism
How did muscle cells evolve
Evolved from molecule switches in which an enzyme or other activity is turned on/off by binding ATP or CTP and undergoing a conformational change
Where did skeletal muscles first appear
Cnidaria
Muscle fiber
Muscle cell
Multinucleate
The bigger the cell, the more nuclei
Myofibrils
Found in muscle fibers, full of actin and myosin filaments
Why is skeletal muscle striated?
Myofibrils are precisely aligned
Electrical nature of muscle
Skeletal muscle is excitable
Myosin
Thick filament, contractile proteins that attach to and exert force on actin filaments
Actin
Thin filaments
Z-line
Structural protein that anchors actin
Sarcomere
Functional unit of skeletal muscle, defined as part from 1 z-line to the next, lined up end to end from tendon to tendon
Crossbridge Cycle
Cycle of binding, ratcheting, and unbinding of myosin head to actin filament
Myosin and actin bond
chemical bond that can only be broken by energy, ATP
ATP in Crossbridge Cycle
Breaks crossbridge and recocks myosin head
Sarcoplasmic Reticulum (SR)
Ca++ reservoir
Tropomyosin
Filament that runs along actin and has a troponin complex attached at regular intervals
T-tubules
transverse tubules, tubes of excitable membrane that course into the fiber
Is muscle myelinated
no
Does skeletal muscle have t-tubules
yes
Does smooth or skeletal muscle have longer actin
smooth
How do skeletal muscle actins run
parallel to the length of the fiber
T-tubule system
Used to get Ap signal simultaneously to all myofibrils for max power in skeletal muscles