Muscle Flashcards

(36 cards)

1
Q

skeletal muscle

A

attached to bone

striated

voluntary

nuclei around periphery

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2
Q

cardiac muscle

A

heart

striated

involuntary - controlled by CNS

nuclei in the center

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3
Q

smooth muscle

A

lacks striation

lines hollow organs

involuntary - controlled by CNS

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4
Q

sarcoplasm

A

cytoplasm of muscle cells

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5
Q

what controls involuntary muscles?

A

CNS

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6
Q

muscle fiber

A

each muscle cell is multinucleated

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7
Q

syncytium

A

multinucleated muscle fiber

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8
Q

endomysium

A

delicate layer of reticular fibers that surrounds muscle fibers (cells)

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9
Q

perimysium

A

thicker CT than endomysium

surrounds fascicles (bundles of muscle fibers)

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10
Q

fascicles

A

bundles of muscle fibers surrounded by perimysium

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11
Q

epimysium

A

sheath of dense CT that surrounds collections of fascicles (the entire muscle)

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12
Q

myofibril

A

structural subunits of muscle fibers

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13
Q

sarcolemma

A

cell membrane

surrounds muscle fiber

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14
Q

sarcoplasmic reticulum

A

smooth ER surrounding myofibrils

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15
Q

thin filaments

A

actin

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16
Q

thick filaments

17
Q

Z line

A

dense outer line

alpha actin

18
Q

M line

A

center of the A band

19
Q

H band

A

just thick filaments

20
Q

sarcomere

A

basic contractile unit of striated muscle

21
Q

titan

A

longest protein known

polypeptide chain stretches along the whole sarcomere

functions as molecular spring

22
Q

What does “decorating” represent?

A

the unipolarity of thin filaments

23
Q

what does ATP function as in skeletal muscle?

A

dissociate myosin from the thin filament

also to move the myosin head via energy from hydrolysis

24
Q

What does Ca control in skeletal muscle?

A

contraction/relaxation by binding to a site on troponin which alters tropomyosin’s position exposing the myosin binding site on actin

25
E-C coupling
binding of acetylcholine from neuron depolarizes sarcolemma and T-tubules which triggers Ca release from SR
26
muscle spindle
sits in perimysium around fascicles special nerve fibers for proprioception
27
Type I slow oxidative
red and slow contracting marathoner
28
Type IIa | fast oxidative
Fast sprinter
29
Type IIb | fast glycolytic
very fast pale muscles weight lifter
30
satellite cell
precursor to myofibers located between cell membrane and basement membrane stimulate for increased growth
31
dystrophin
is thought to link laminin, which resides in the external lamina of the muscle cell, to actin filaments. Absence of this protein is associated with progressive muscular weakness, a genetic condition called Duchenne’s muscular dystrophy. Dystrophin is encoded on the X chromosome, which explains why only boys suffer from Duchenne’s muscular dystrophy. Recently, characterization of the dystrophin gene and its product has been clinically important
32
Unique to cardiac muscle
cardiac nuclei in middle cardiac functional syncytium T-tubules are larger intercalated disks with adherins, desmosomes, and gap junctions
33
functional syncytium
cardiac muscle can have 2 nuclei but intercalated disks prevent it from being really multinucleated like skeletal muscle
34
syncytium
skeletal cell - multinucleated
35
atrial granules
found in atria of heart release ANF and BNF by exocytosis
36
Calmodulin
what Ca binds to in smooth muscle activates a myosin light chain kinase