Muscle-microanatomy Flashcards

(41 cards)

1
Q

This is the cytoplasm of muscle cells , contains myoglobin and glycogen

A

sarcoplasm

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2
Q

This is the plasma membrane of muscle cell

A

sarcolemma

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3
Q

A highly specialized smooth endoplasmic reticulum of a muscle cell regulating calcium flow

A

sarcoplasmic reticulum

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4
Q

cylindrical multi nucleated cells

A

myofibers

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5
Q

contractile elements composed of repeating sections of myofilaments .

A

myofibrils

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6
Q

known as Thick myosin and thin actin

A

myofilaments

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7
Q

dense irregular connective tissue surrounding muscle

A

epimysium

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8
Q

surrounds smaller bundles of muscle (fascicles)

A

perimysium

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9
Q

individual myocytes are surrounded nu reticular fibers forming the..

A

endomysium

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10
Q

contractile or functional unit of myocyte

A

sarcomere

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11
Q

At a full contraction, these lines will be drawn close to each other.

A

z line

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12
Q

This line is located in the H band(H band within A band)

A

m line

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13
Q

corresponds to the area where thick and thin filaments overlap(dark band)

A

A-band

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14
Q

Composed of only thin actin filaments(pale band)

A

I-band

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15
Q

This band is located in the center of A band and M line is located within it.

A

H band

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16
Q

Protein that lies within the groove between actin filaments in muscle tissue. In a relaxed muscle this protein blocks the attachment site for the myosin cross bridge , preventing contraction

A

tropomyosin

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17
Q

complex protein that works with tropomyosin

18
Q

a deep invagination of the sarcolemma that allows depolarization of the membrane to quickly penetrate to the interior of the cell allowing calcium release from the sarcoplasmic reticulum

A

T- tubule or transverse tubule

19
Q

The actin filaments of contractile units are attached to ___ ____ The intermediate filaments are connected to other intermediate filaments via ___ ___, which eventually are attached to adherens junctions in the cell membrane of the smooth muscle cell, called the sarcolemma.

20
Q

These attach cardiac muscle cells to each other , providing strength and the ability to function as a syncytium

A

intercalated discs

21
Q

These cells are positioned between basal lamina and sarcolemma of muscle cell , retain mitotic potential and accomplish in some form of repair.

A

myosatellite cells

22
Q

These are modified cardiac muscle cells with 1 or 2 nuclei , sparse and restricted to periphery of the cell

A

purkinje fibers

23
Q

What is the germ layer origin of muscle? and what shape are muscle cells?

A

muscle cells are spindle shaped and originate from the mesoderm (myoblast)

24
Q

what are the 3 types of muscle?

A

skeletal,smooth , cardiac

25
This type of muscle: - makes up 50% body weight - tongue , masseter (cheek) and heart are strongest muscles of the body - myocytes contain MULTIPLE PERIPHERALLY LOCATED NUCLEI - STRIATIONS are seen in myocytes when cut in longitudinal section - VOLUNTARY muscles - limited regeneration capacity- satellite cells are b/w basal lamina and sarcolemma of muscle , these cells have mitotic potential, therefore they can accomplsh some repair
Skeletal muscle
26
What development is the following? - mesenchymal cells align and fuse together forming multinucleated tubes(myotubes) - myotubes differentiate forming functional myofilaments and the nuclei are displaced against plasma membrane. - some cells do not differentiate and remain mesenchymal cells (satelitte cells function in muscle repair)
skeletal muscle development
27
This muscle is surrounded by dense irregular CT layer(epimysium) - whole muscle is made up of smaller bundles called fascicles surrounded by perimysium - each fascicle is made up of many muscle cells - myofibers contain cylindrical bundles of myofibrils which in turn contain many smaller bundles of myofilaments (endomysium surrounds individual myocytes)
skeletal muscle organization
28
this type of muscle contains a single cell with one central nucleus
cardiac muscle | Cardiomyocyte=myocardiocyte=cardiac myocyte
29
this type of muscle is cross striated and lacks the ability to regenerate. Contains intercalated discs- which attach ___muscle cells to each other , providing strength and ability to function as a syncytium.
cardiac muscle
30
cardiac muscle contains ___-___: longitudinal element for communication , allowing electrical impulse and _____: transverse element acting as a strong anchor
gap junctions and desmosomes.
31
cardiac muscle contains sarcoplasmic reticulum and many _____ present (requires abundant oxygen). -cardiomyocytes are ___ and conductile
mitochondria | contractile
32
- These are modified cardiac muscle cells with 1-2 nuclei - myofibrils are sparse and restricted to periphery of cell - arranged in groups
purkinje fibers
33
- single centrally located nucleus - nostriations or myofibrils,actin/myosin present but no order to them - desmosomes and gap junc. are seen - no T-tubules - spindle shaped FUSIFORM cells surrounded by basal lamina and reticular fibers - single central nucleus-cigar shaped - parasympathetic and sympathetic innervation - CONTRACTION INVOLUNTARY
smooth muscle
34
type of smooth muscle found in visceral organs, cells behave like syncytium contracting in a network, sparse nerve innervation but cell communicate via multiple gap junctions
single smooth muscle
35
type of smooth muscle found in iris of eye , precise contraction, individual innervation of each myocyte, lack gap junctions which makes them function individually
multi-unit smooth muscle
36
Functions of smooth muscle: - _____ wave like contractions ex. gastrointestinal tract - ____ ___ - contraction alters blood flow and important in blood pressure - ____ - urinary bladder, uterus - ___ (minor role)
peristalsis vascular dynamics propulsion secretion
37
in smooth muscle regeneration is ___ , new smooth muscle cells may be derived from mesenchymal cells. Repair in smooth muscle is completed by ___ tissue formation formed by fibroblasts
limited, scar tissue
38
smooth muscle is seen in the wall of ___ organs - tunica___ - tunica_____
luminal organs tunica mucosa and tunica submucosa
39
what are the two types of non muscle contractile cells
myoepithelial cells and myofibroblasts
40
these non-muscle contractile cells have ectodermal origin , contain actin/myosin, smiliar to smooth muscle, can be stimulated by horomones(mammary gland) , basketlike shape(encloses clusters of glandular cells), and are found in salivary, mammary and lacrimal glands
myoepithelial cells
41
These non muscle contractile cells play a role in wound contraction:
myofibroblast