muscle relaxants Flashcards Preview

Narcotics: Pain Mgmt and Addiction > muscle relaxants > Flashcards

Flashcards in muscle relaxants Deck (33):
1

cyclobenzaprine brands

Flexeril
Amrix

2

flexeril
amrix
generic

cyclobenzaprine

3

cyclobenzaprine MOA

skeletal muscle relaxant (antispasmodic)

- works at brainstem level

- anticholinergic activity
- potentiates NE

4

how is flexeril cyclobenzaprine cleared?

renal drug

5

t/f flexeril effective in spasticity due to spinal cord or cerebral injury, cerebral palsy, ?

no not effective

6

cyclobenzaprine ADR

- think anticholinergic effects
- dry mouth
HA
somnolence

7

flexeril, amrix drug interactions

- MAOI: fatal interaction
- ETOH other depressants

- increase risk sz with tramadol!!

8

warnings cyclobenzaprine

- urinary retention
- increases IOP (acute angle closure glaucoma)

9

who concerned increased IOP with cyclobenzaprine

those at risk for acute angle closure glaucoma

- farsighted hyperopes
- women
- asian
- older

10

carisoprodol (Soma) is a muscle relaxant however don't rx because

high abuse potential
MOA not fully understood

rare ADR: transient quadriplegia

11

metaxalone (skelaxin) MOA

not well known
- CNS depression
- no direct muscle effect

12

metaxalone ADR

N/V GI upset
leukopenia
hemolytic anemia
jaundice

13

methocarbamol brand

robaxin

14

baclofen brands

kemstro, lioresal, gablofen

15

baclofen MOA

GABA analog
inhibits reflexes at spinal level

16

___ is indicated for spasms due to multiple sclerosis, trigeminal neuralgia, spinal cord injury

baclofen (kemstro, gablofen, lioresal)

17

baclofen potential helps ___

treat addiction
- opioid
- cocaine
- ETOH

18

orphenadrine brand

norflex
norgesic

19

orphenadrine moA

analgesic
anticholinergic
(ADR: blurr vision, mydriasis, increased weakness, N/V etc)

20

chlorzoxazone brands

parafon forte
lorzone

21

chlorzoxazone MOA

inhibits multisynaptic reflex arcs that produce spasms

- relieves pain, increase mobility

22

chlorzoxZONE VS ORPHENADRINE

chlorzoxazone is less anticholinergic


better well tolerated

23

what lab get prior to start on chlorzoxazone

LFT
can cause idiosyncratic hepatotoxicity

24

what is glucosamine sulfate

works well with horse RA

-

25

MOA glucosamine sulfate

amino sugar that is part of cartilage proteoglycans, found in tendons, cartilage, ligaments, synovial fluid etc


- stimulates metabolism of chondrycytes in articular cartilage

- improves pain and function

26

what warning with glucosamine hydrochloride

make sure pt does not have shellfish allergy as it comes from seashells

27

topical methyl salicylate (wintergreen oil) topical pain relief worry about

ASA allergy
watch with anticoagulants
short term use no longer than 1 week

28

how does topical capsaicin work

- counter irritant
- creates local irritation/ inflammation to relieve inflammation in underlying or adjacent tissues

29

menthol is active ingredient in

peppermint

30

menthol uses

- orally for GI complaints
- antispasmodic for IBS
- relaxes LES
- lower GI motility
- topically for pain

ADR: heartburn, N/V, contact dermatitis

31

menthol rub abuse

- applying to eye
- huffing vicks vapor rub etc

32

camphor is what

topical antitussive / analgesic

- can cause resp failure, sz

33

post-herpetic neuralgia topical recommended

capsaicin
- stimulates TRPV1 which stimulates pain receptors and brings relief to area depletes substance P