Muscles Flashcards

(35 cards)

1
Q

What is tension

A

The force that a muscle exerts on the joint when it is contracting is called the tension of the muscle

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2
Q

What is load

A

The force that is exerted on a muscle by an object is called the load of the muscle

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3
Q

What happens if tension does not exceed load

A

The muscle will either remain at the same length or it will lengthen

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4
Q

What are the types of muscular contraction

A

Shortening (concentric) contraction
Isometric contraction
Lengthening (eccentric) contraction

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5
Q

What is the mechanical response of a muscle fibre to a single action potential

A

A twitch

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6
Q

What is the latent period

A

Comes after the action potential before the tension in the muscle fibre begins to increase

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7
Q

What is the contraction time

A

The time interval from the beginning of tension development (at the end of the latent period) to the peak tension

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8
Q

A shortening (concentric) contraction, an increasing load causes…

A
  • the latent period to increase
  • the velocity of shortening to slow down
  • the total duration of the twitch to become shorter
  • the distance shortened to become less
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9
Q

What happens when load increases to the point where the muscle is not abele to move it

A

The contraction becomes isometric

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10
Q

What happens when load increases beyond the peak tension that a muscle can produce

A

The contraction becomes lengthening (eccentric)

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11
Q

What is summation

A

The increase of muscle tension from successive action potentials

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12
Q

What is temporal summation

A

When twitch doesn’t have the time to go back to normal state

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13
Q

What is tetanus

A

When successive stimulations result in a sustained contraction

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14
Q

What is unfused tetanus

A

When the muscle fibre has time to partially relax before the next stimulation
The development of tension oscillates

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15
Q

What is fused tetanus

A

When the muscle fibre has no time to relax between stimulations
The development of tension is continuous and smooth

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16
Q

Muscle fibre types

A

IIx - fast-twitch, fast-glycolytic fibres
IIa - intermediate fibres, fast-oxidative glycolytic fibres
I - slow-twitch, slow-oxidative fibres

17
Q

What does muscle contraction speed depend on

A

The rate of cross bridge cycling, which depends on the myosin heavy chain isoform

18
Q

Mechanisms involved in muscle fatigue

A
  • Conduction failure
  • Lactic acid build up
  • Inhibition of cross-bridge cycling
  • Fuel substrates
  • Central command fatigue
19
Q

What does a motor unit do

A

Provides interaction between nervous system and muscles

20
Q

What does an action potential do

A

Propagates over muscle fibres to case contraction

21
Q

What is excitation-contraction coupling

A

The sequence of events by which an action potential in the plasma membrane activate the force-generating mechanisms

22
Q

How long does an action potential last in a skeletal muscle fibre

23
Q

What is going on in a relaxed muscle

A

Low ca2+
Cross bridge cannot bind with actin as tropomyosin is covering the binding site

24
Q

What is happening in an active muscle

A

High ca2+
Ca2+ binds to troponin -> tropomyosin moves away from cross-bridge binding site -> actin binds to cross bridge

25
What proteins are responsible for linking the membrane action potential with calcium release in the cell
Dihyropyridine (DHP) receptor Ryanodine receptor
26
What is ATPase
An enzyme which determines the speed of ATP hydrolysis and resulting sarcomere shortening velocity
27
What are the molecular changes for endurance phenotype characterised by
- increased mitochondrial mass - increased oxidative enzymes - decreased glycolytic enzymes - increased slow contractile and regulatory proteins - decrease in fast-fibre area
28
Molecular changes to high resistance training
- increases in wet mass - increase in fibre cross-sectional area - increase in protein content - increase in RNA content
29
What is hypertrophy
Increase in muscle fibre size due to the addition of contractile proteins in the muscle cell
30
What does muscular hypertrophy depend on
Initial strength Duration of the training programme Training technique
31
What are the components of resistance training
- time under tension - volume - velocity - exercise order - recovery between sets - frequency - exercise type
32
What is hyperplasia
Increase in the number of muscle fibres
33
Role of creating phosphate
Provides energy very fast to form ATP from ADP but only lasts 1-2 sec
34
What is glycolysis
Energy from glucose in the absence of oxygen
35
What is oxidative phosphorylation
Energy from glucose or fat in the presence of oxygen