Muscles Part 1 Flashcards

1
Q

Muscle Tissue is derived from

A

Mesoderm

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2
Q

Three types of muscle tissue

A

Skeletal
Cardiac
Smooth

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3
Q

Skeletal Muscle Tissue contains

A

40% of body mass
multi-nucleated cells
quick twitch, short contractions

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4
Q

Cardiac Muscle Contains

A

cells are short and branched
striations
intercalted discs
intermediate twitch

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5
Q

Smooth Muscle Tissue Contains

A

Lack striations
Slow twitch
long contrations

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6
Q

Functions of Skeletal Muscle Tissue

A

Produces Skeletal Movement
Maintains Body Posture and Positon
Supports Soft Tissues
Guards Entrances and Exits
Maintains body temperature
Provides Nutrient Reserves

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7
Q

A Single Skeletal Muscle is composed of

A

Large bundles called fascicles

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8
Q

Fascicles are composed of

A

Numerous Muscle Cells also called Muscle Fibers

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9
Q

Muscle Fiber is composed of

A

Myofibrils

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10
Q

Myofibrils are composed of

A

Two Contractile proteins called myofilaments

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11
Q

Myosin

A

Thick Myofilaments

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12
Q

Actin

A

Thin myofilaments

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13
Q

Sarcomeres

A

Myocin and Actin are arranged in an overlapping pattern creating hundreds to thousands of these

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14
Q

Epimysium

A

Dense Layer of Collagen Fibers surrounds the entire muscle
Separates Muscle from surrounding tissues and organs
Connected to Deep Fascia

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15
Q

Perimysium

A

Fibrous layer that divides muscle fibers into a series of bundles called fascicles
Possesses blood vessels, nerves, collagen and elastic fibers

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16
Q

Endomysium

A

Delicate connective tissue that surrounds individual skeletal muscles/fibers

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17
Q

Tendon

A

End of skeletal muscles collagen fibers merge into this

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18
Q

Aponeurosis

A

Broad sheet at end of muscles, anchor to bone

19
Q

Cytoplasm of a muscle cell is called

A

Sarcoplasm

20
Q

Myogobin

A

Large amounts in muscle cells
Important protein in storage of oxygen

21
Q

Plasma Membrane of a muscle cell is called

A

Sarcolemma

22
Q

Transverse Tubules (T tubules)

A

Invaginations of the sarcolemma that extend deep into the sarcoplasm at right angles to cells surface
Allow electrical impulses generated at the surface to travel into the cell’s interior

23
Q

Sarcoplasmic Reticulum (SR)

A

Similar to smooth ER of other cells
Forms tubular network surrounding each myofibril
Membrane contains ion pumps that move Calcium from cytosols into the ER

24
Q

Calsequestrin

A

Protein located in the SR that calcium ions bind to

25
Triad
One T-Tubule that has a terminal cisterna on either side
26
Terminal Cisterna
Tubules of SR that are enlarged and form chambers to store calcium ions
27
Sarcomere
Functional/contractile unit of skeletal muscle Resting length of about 2 um Composed of specific arrangements of myofilaments of actin and myosin
28
A Band
Dense region of sarcomere that contains overlapping thick (myosin) and thin (actin) filaments
29
I Band
Either side of A band Only contains thin filaments (actin)
30
H Band
In the middle of the A- Band Only contains Thick filaments (myosin)
31
M Line
Located in Middle of H band Anchors central portion of each thick filament
32
Z Lines
Mark Boundary between adjacent sarcomeres
33
Actinins
Located in Z line Proteins Anchor thin filaments of adjacent sarcomeres
34
Numbers 1-5
1 - Muscle Fiber Nucleus 2 - Motor Neuron Axon 3 - Axon Branches 4 - Motor Neuron Endplate 5 - Myofibril of muscle fiber
35
Numbers 6-10
6 Synaptic Cleft 7 Folded Sarcolemma 8 Acetylcholine 9 Mitochondria 10 Synaptic Vesicles
36
Thin Filaments of Actin are composed of
F-Actin Filamentous Actin G-Actin Globular Actin Nebulin Tropomyosin Troponin
37
F-Actin
Filamentous - Twisted strand composed of two rows of 300-400 individual molecules of G-Actin
38
G-Actin
Globular Rounded, compact molecule of protein that possesses an active site where one myosin molecule can bind
39
Nebulin
Long strand of protein that extends along the F-Actin strand in the cleft between the rows of G-Actin molecules Helps stabilize the F-Actin strands
40
Tropomyosin
Double-stranded protein that covers over the active sites of the G-Actin in a resting muscle. Prevents interaction of actin and myosin
41
Troponin
Three globular subunits, strategically placed along tropomyosin
42
Action of Calcium biding to Troponin
Troponin changes shape which causes tropomyosin to swivel, revealing active site on G-Actin so myosin and actin can form a cross bridge
43
Myosin
Myosin Molecules - pair of myosin subunits twisted around each other Tail portion connected to a free head portion Tail and Free head connected by hinge that allows head to swivel Single filament has about 300 molecules twisted together - tails point to M Line, heads arranged in a spiral facing the thin filaments At core is a thick elastic filament of Tintin which recoils after stretching
44
Synaptic Terminals
Axon of each motor neuron branches to form numerous cellular extensions