Muscular (E3) Flashcards

1
Q

3 layers of skeletal muscle

A
  1. Epimysium
  2. Perimysium
  3. Endomysium
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2
Q

Components of myofibrils

A

Sarcomere composed of thin and thick filaments and Z & M lines or discs

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3
Q

Thick filaments

A

Composed mainly of myosin which is made up of 2 heavy chains and 4 light chains

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4
Q

Thin filaments

A

Composed of actin, nebulin, troponin, and tropomyosin

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5
Q

Muscle tone

A

Resistance to stretch exhibited by a relaxed muscle
- due to baseline calcium in the cytosol

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6
Q

Intrinsic muscle tone in smooth muscle

A

Due to baseline Ca+ levels in the cytosol causing low level tension activity

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7
Q

Alpha motor neurons

A

-innervate skeletal muscle fibers
-cell bodies are located in the brainstem and spinal cord

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8
Q

T/F: all neuromuscular junctions are excitatory.

A

True

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9
Q

Botulinum toxin

A

Neurotoxin released from clostridium botulinum
-blocks Ach release

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10
Q

Curare

A

-blocks Ach receptors
-similar in action to nondepolarizers

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11
Q

T/F: a muscle cell has multiple nuclei

A

True

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12
Q

Satellite cells

A

Undifferentiated stem cells that repair damaged or destroyed skeletal muscle fibers

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13
Q

Skeletal muscle

A

-attached to bones by tendons

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14
Q

Sarcomere

A

One unit of thin and thick filaments

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15
Q

Wide dark bands in the middle

A

A band

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16
Q

Light bands

A

I bands

17
Q

Narrow dark bands in middle

A

H zone (inside A band)
M line (inside H zone)

18
Q

Sarcoplasmic reticulum

A

-same as endoplasmic reticulum in most cells
-store large quantities of Ca+

19
Q

Sarcolemma

A

-plasma membrane of muscle cell
-propagates action potential

20
Q

Contraction

A

Activation of the force generating sites within muscle fibers (the cross bridges)

21
Q

Motor unit

A

A motor neurons and the muscle fibers it innervates

22
Q

How is the length of a skeletal muscle cell related to the force it can generate?

A

Skelta muscle cells generate the most force when the contraction occurs at an intermediate length

23
Q

Phases of muscle twitch

A

Latent period
Contraction phase
Relaxation phase

24
Q

Latent period

A

Time elapsed from the application of a stimulus to the beginning of the contraction

25
Q

Contraction period

A

Cross bridges are active in the muscle shortens if tension is great enough to overcome the load

26
Q

Relaxation period

A

Active transport of calcium back into the sarcoplasmic reticulum and degradation of acetylcholine

27
Q

Single twitch

A

Same size twitches if completely relaxed between

28
Q

Twitch summation

A

Muscle fiber restimulated before completely relaxed, second twitch added to first twitch

29
Q

Tetanus

A

Muscle fibers stimulated so rapidly. It does not relax, maximus is saying contraction occurs

30
Q

Train of four responses

A

Absent - 100
One twitch - 90
Two twitches - 80
Three twitches -75
Four twitches -0-75

31
Q

Central command fatigue

A

Appropriate regions of the cerebral cortex fail to send excitatory signals to them motor neurons

32
Q

Oxidative fibers

A

-more mitochondria
-more blood flow
-long term contractions (posture)

33
Q

Glycolytic fibers

A

-few mitochondria
-large store of glycogen
-quick activity bursts
-lack myoglobin (white muscle fibers)