musculo week 2 vocab terms Flashcards
(23 cards)
bone Matrix
organic components: 40% dry weight of bone, collagen, proteoglycans, glycoproteins, and phospholipids
Bone Types
normal bone is lamellar. immature or pathologic bone is woven, not stress oriented. mature lamellar bone is cortical or cancellous.
Cancellous Bone
spongy or trabecular. fractures generally progress at 6 weeks. examples are calcaneus, vertebral body, radius, pelvis, and tibia
cortical bone
AKA compact bone
located in the diaphysial portion of long bones
80-9-% of volume is calcium. Makes up80% of skeleton
osteoblasts
(Bone formation)
distinct cells that form bone matrix and synthesize type 1 collagen
-large volume of endoplasmic reticulum, Golgi apparatus, and mitochondria
-responsible for synthesis, deposition and mineralization of bone; derived from bone marrow and pro collagen
osteoclasts
(bone resorption)
giant cell multinucleate bone resorption cells
-produce hydrogen ions, which lower the pH environment
Woven Bone
structurally immature, fragile, weak
-random disorganized collagen arrangement
-allows strength in all directions, which no preferred strength in one direction
- function is to provide temporary quick acting mechanical support for injured skeletal tissue
piezoelectric effect
a negative electrical charge toward the concave side of a force applied. (stimulates osteoblasts)
a n electropositive charge is seen on the tension or convex side (increase osteoclast)
remodeling
normal dynamic process of bone synthesis and resorption
repair
primary callus forms in 2 weeks. soft callus involving endochondral ossification occurs if fracture is not in continuity. Amount of of callus is indirectly proportional to degree of immobilization. Primary cortical healing occurs with immobilization and near-anatomic reduction.
osteocytes
osteoblasts that are embedded within newly formed mineralized bone matrix
-90% of mature skeletal tissue and function metabolically
Remodeling
Osteomalacia
Poor absorption of calcium that leads to decreased bone mineralization
Fracture
any abnormal disruption in the normal anatomic continuity of a bone, an epiphyseal plate, or a cartilaginous joint surface
incomplete fracture
hair line or greenstick fractures
complete fracture
traverses the bone entirely
angiogenesis
physiologic process during healing of bodily tissues which new capillary blood vessels are formed
articular cartilage
concentration of collagen, proteoglycans, and wanter, influence tensile forces, compression, shear, and permeability
chondrogenesis
intrinsic cartilage repair
deep zone
largest part of articular cartilage
fibrocartilage
cartilage that naturally makes up meniscus and labrum. made of mostly type 1 collagen
hydrophilic
quality of a molecule that causes it to bind to and attract water
menisci
semilunar shaped fibrocartilage tissues in the knee that act as a mechanical buffer between the load-bearing surfaces of the tibia and femur