Musculoskeletal

Question 1

Which conditions cause a sacroiliitis?

Answer 1

Seronegative arthropathies including:

• Ankylosing spondylitis
• Reiter syndrome (reactive arthritis)
• Enteropathic/IBD
• Psoriatic arthritis

Question 2

What are the disease modifying agents used to treat ankylosing spondylitis?

Answer 2

Adalimumab, etanercept

Question 3

Anti-cardiolipiin, anti-B2 glycoprotein, lupus anticoagulant

Answer 3

Antiphospholipid syndrome

Question 4

Anti-smooth muscle, anti-LKM, anti-SLA

Answer 4

AI hepatitis

Question 5

Anti-Rh

Answer 5

AIHA

Question 6

Anti-GpIIb/IIIa

Answer 6

AI thrombocytopenia purpura

Question 7

p-ANCA

Answer 7

eGPA (Churg Strauss), microscopic polyangiitis

Question 8

c-ANCA

Answer 8

GPA Wegener’s granulomatosis

Question 9

Anti-TTG, anti-endomysial

Answer 9

Coeliac

Question 10

Anti-endomysial

Answer 10

Dermatitis herpetiformis

Question 11

Anti-Jo1

Answer 11

Dermatomyositis, polymyositis

Question 12

Anti-GBM

Answer 12

Good pasture’s

Question 13

Anti-TSHR

Answer 13

Graves

Question 14

Anti-TPO, TG

Answer 14

Hashimoto’s

Question 15

Anti-centromere

Answer 15

CREST (limited cutaneous scleroderma)

Question 16

Anti-nAChR

Answer 16

Myasthenia gravis

Question 17

Anti-IF, gastric parietal cell

Answer 17

Pernicious anaemia

Question 18

Anti-mitochondrial

Answer 18

PBC

Question 19

Anti-CCP RhF

Answer 19

RhA

Question 20

Anti-Ro, La, RhF

Answer 20

Sjogren’s

Question 21

Anti-dsDNA, anti-histone, Sm, Ro, La

Answer 21

SLE

Question 22

Anti-GAD, anti-B islet

Answer 22

T1DM

Question 23

c-ANCA

Answer 23

Wegener’s granulomatosis (GPA)