Musculoskeletal Tumors Flashcards
(20 cards)
Painful vascular lesion of unknown etiology, PAIN at NIGHT, RELIEVED by ASPIRIN,
Osteoid osteoma
Transient failure of ossification of physeal cartilage and vyst formation. RADIOLUCENT with DISTINCT borders
Unicameral bone cyst
Expansile blood filled intramedullary lesion, ECCENTRIC EXPANSILE LYTIC LESION with HONEYCOMBED bone septae and DISTINCT BORDERS.
Aneurysmal bone cyst
Replacement of normal bone with fibrous tissue
Fibrous dysplasia
Physeal carilage that did not ossify and gets trapped in bone. Also, the most common primary tumor of the hand
Enchonroma
Seen in the metaphysis in the 2nd and 3rd decades of life, composed of woven bone ina rich fibro vascular stroma, differentiated from osteosarcoma by DISTINCT BORDERS ON XRAY and ABSENCE OF ATYPIA IN OSTEOBLASTS ON HISTOPATH.
OSTEOBLASTOMA
Fairly common in filipinos, 3rd to 4th decade of life, painful, common around distal radius, distal femur, proximal tibia.
Lystic, epiphyseal/metaphyseal lesion, expansile with neocortex formation.
Benign, aggressive tumor. Expansile with neocortex formation, expand locally and soread to lungs.
giant cell tumor
Common xray finding of BENIGN BONE TUMORS
Distinct borders on xray
Local tissues not invaded on MRI or enhanced CT
No evidence of mets
most common primary malignant bone tumor.
Peaks in the young and old, usually with pagets dse or those who have recieved radiotherapy for other disorders.
Very aggressive, bone forming tumor with permeative borders
Osteosarcoma
Very aggressive malignant round cell tumor in children( 2nd to 3rd decade in life)
Relatively rare. Malignant. Lytic with extensive bone destruction, permeative birders.
Ewings sarcoma
Elements of very rapid aggressive growth
Codman’s triangle
Onion peel
Sunburst
Cartilage forming tumor, malignant, that may occur primarily or secondarily after preexsiting benign tumor.
Cotton ball or wool-like. Common in the pelvis and ends of long bones, after 4th decade of life. Resistant to chemotherapy and radiotherapy. POOR PROGNOSIS
Chondrosarcoma
Malignant neoplasm of epithelial origin
Carcinomas
Inflammatory markers
CSR ( c reactive protein) esr ( erythrocyte sedimentation rate)
Enzyme concentrated in the liver and bile ducts,( liver disorders; bile obstruction)
Bone (active osteoblastic activity)
Kidney
Placenta
Serum alkaline phosphatase
PSA 4x normal level. Suspect ?
Prostate cancer
CA 27.29 and CA15-3 are markers for?
Breast malignancy
CEA or carcinoembryonic antigen and CA 19-9 are markers for?
GI/ tract colon malignancies
A moth eaten appearance on xray suggests?
Malignancy
Normal bone tissue in an abnormal location
Bone island
