MUSKULOSKELETAL Flashcards Preview

T year LOBs medicine > MUSKULOSKELETAL > Flashcards

Flashcards in MUSKULOSKELETAL Deck (12):
1

what are signs of osteoarthritis?

- mild to moderate pain which improves with rest
- stiffness lasting under 30 minutes
- gradual in onset and progressive

2

what joints are involved in osteoarthritis?

Weight bearing joints mainly the hips and knees

3

what are signs of rheumatoid arthritis?

- worse after resting
- systemic features of fatigue and weight loss

4

what is the joint involvement in rheumatoid arthritis?

symmetrical polyarthritis

5

what blood tests can be done in rheumatoid arthritis?

- FBC can show anaemia
- raised ESR
- IgM Rf in the blood

6

What is a definition of polymyalgia rheumatic (pmr)?

An inflammatory syndrome that manifests as pain and morning stiffness involving the neck, shoulder girdle in individuals over 50

7

what are clinical features of PMR?

- symmetrical limb girdle pain
- stiffness worse in the morning
- malaise, fever, weight loss
- bilateral stiffness of the shoulder, neck and spine
- difficulty rising from sitting position

8

What are clinical features of giant cell arteritis?

Headache often in the temporal regions
Malaise, weight loss, fever, night sweat
- jaw claudication
- temporal tenderness

9

how is PMR diagnosed?

The bird criteria:
Three or more of: bilateral shoulder pain weakness, duration of onset under 2 weeks, initial ESR>40 morning stiffness lasting over 1 hour, aged over 65, depression, weight loss

10

what histological changes are there in GCA?

- infiltration of CD4 T cell
Macrophages and giant cells in the vessel wall
granulomatous inflammation of the intima and media
breaking of the internal elastic lamina

11

what is management of PMR?

prednisolone 10mg
calcium/vit D/ bisphosphonates to protect from steroids

12

what is the management of GCA?

60mg prednisolone