Mutation

Question 1

What caused mutation

Answer 1

DNA is copied when cells devide, and error occurs, leading to a change in base sequence.

Question 2

Haemophilia

Answer 2

The body’s first response to bleeding is to seal the wound to prevent blood loss.
A genetic disease that causes blood to fail to clot properly.

Question 3

What caused Haemophilia?

Answer 3

A base substitution, where C is replaced by T in the DNA. (This creates a stop codon in the mRNA rather than coding for the amino acid arginine.)

Question 4

Mutation

Answer 4

Changes in base sequence of DNA that leads to altered mRNA which can lead to altered amino acid sequence

Question 5

Substitution

Answer 5

Mutation that exchanges one base for another

Question 6

Insertion

Answer 6

Extra base pairs inserted into a new place in the DNA, resulting in base pairs after insertion to be shifted down

Question 7

Deletion

Answer 7

Section of DNA is deleted, resulting in base pairs after the deletion to move up

Question 8

Duplication

Answer 8

A section of DNA copied one or more times

Question 9

Missense

Answer 9

Single nucleotide base substitution that alters a codon so it codes for a different amino acid

Question 10

Nonsense

Answer 10

Stop codon inserted early which results in premature termination of protein