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MTAP > MYCOLOGY (Systemic Mycoses) > Flashcards

MYCOLOGY (Systemic Mycoses) Flashcards

(60 cards)

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1
Q

Southeast Asia

What systemic mycosis?

A

Talaromycosis (Penicilliosis)

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2
Q

Central & South America

What systemic mycosis?

A

Paracoccidioidomycosis

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3
Q

Southwestern US, Mexico

What systemic mycosis?

A

Coccidioidomycosis

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4
Q

Mississippi & Ohio River valleys

What systemic mycosis?

A

Histoplasmosis

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5
Q

Mississippi & Ohio River basins, St. Lawrence River

What systemic mycosis?

A

Blastomycosis

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6
Q

What systemic mycosis?

Yeast-like cells inside macrophages, red diffusible pigment in culture

A

Talaromycosis (Penicilliosis)

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7
Q

What systemic mycosis?

Yeast with “pilot wheel” appearance

A

Paracoccidioidomycosis

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8
Q

What systemic mycosis?

Spherules containing endospores

A

Coccidioidomycosis

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9
Q

What systemic mycosis?

Small intracellular yeast (2-5 µm) in macrophages

A

Histoplasmosis

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10
Q

What systemic mycosis?

Broad-based budding yeast, DNA probe confirmation

A

Blastomycosis

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11
Q

Also known as Gilchrist disease, North American blastomycosis, Chicago disease.

A

Blastomycosis

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12
Q

Affects primarily middle-aged men due to occupational/recreational exposure to soil.

A

Blastomycosis

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13
Q

Often asymptomatic; primary infections may cause flu-like symptoms.

Progressive pulmonary disease presents with:

Cough, weight loss, chest pain, fever.

May progress to ulcerative skin and bone lesions.

A

Blastomycosis

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14
Q

causative agent of Blastomycosis

A

Blastomyces dermatitidis

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15
Q

Blood agar, 37 degree celsius

A

Blastomyces dermatitidis

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16
Q

Pines medium,
Glucose-cysteine blood,
BHI-blood,
37 degree celsius

A

Histoplasma capsulatum

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17
Q

BHI-blood, 37 degree celsius

A

Paracoccidioides brasiliensis

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18
Q

MOT: Inhalation of arthroconidia

what causative agent?

A

Coccidioides immitis

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19
Q

MOT: Inhalation of microconidia (bird/bat guano)

what causative agent?

A

Histoplasma capsulatum

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20
Q

Mariner’s wheel yeast cells

A

Paracoccidioides brasiliensis

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21
Q

Valley fever

A

Coccidioides immitis

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22
Q

erythema nodosum

A

Coccidioides immitis

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23
Q

Pulmonary calcifications, chronic lung disease

A

Histoplasma capsulatum

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24
Q

Ulcerative mucosal lesions, lymphadenopathy, adrenal involvement

A

Paracoccidioides brasiliensis

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25
Disseminated disease in AIDS patients, cutaneous lesions
Penicillium marneffei
26
Most virulent of all human mycotic agents.
Coccidioides immitis
27
Erythema nodosum (desert bumps), erythema multiforme (valley fever), arthritis (desert rheumatism) Allergic manifestations of what fungi
Coccidioides immitis
28
Disseminated disease (1% of cases): Higher risk in Filipinos, Black individuals, and pregnant women. Commonly affects the meninges.
Coccidioides immitis
29
Endemic areas: Lower Sonoran life zone (arid regions).
Coccidioides immitis
30
Initial colonies: White to gray, moist, glabrous → Develop aerial mycelium → Mature colonies tan, brown, or lavender.
Coccidioides immitis
31
Common in immunocompetent individuals, residual calcifications in lungs, liver, spleen.
Histoplasma capsulatum
32
Histoplasma capsulatum Chronic pulmonary histoplasmosis: Common in ___ patients.
COPD
33
Endemic areas: Ohio, Missouri, Mississippi River valleys.
Histoplasma capsulatum
34
Reservoir: Soil with high nitrogen content (bat/bird guano).
Histoplasma capsulatum
35
Resembles Candida glabrata (differentiated via FA techniques or culture).
Histoplasma capsulatum
36
Histoplasma capsulatum Resembles Candida glabrata (differentiated via ___ techniques or culture).
FA
37
Serology: EIA: Antigen detection from blood, CSF, urine. Antibody tests: Complement fixation, immunodiffusion, latex agglutination. Most useful: Rising titers in complement fixation & immunodiffusion.
Histoplasma capsulatum
38
22°C: White to brownish mold.
Histoplasma capsulatum
39
H. capsulatum var. duboisii (Central Africa) → ___ H. capsulatum var. farciminosum → ___
H. capsulatum var. duboisii (Central Africa) → Skin & bone disease. H. capsulatum var. farciminosum → Epizootic lymphangitis in horses/mules.
40
Ulcerative granulomatous lesions (buccal, nasal, GI mucosa).
Paracoccidioides brasiliensis
41
Other manifestations: Mediastinitis, pericarditis, mucocutaneous lesions.
Histoplasma capsulatum
42
South American blastomycosis
Paracoccidioidomycosis
43
Brazilian blastomycosis
Paracoccidioidomycosis
44
Lutz-Splendore-Almeida disease
Paracoccidioidomycosis
45
Gilchrist disease
Blastomycosis
46
Chicago disease
Blastomycosis
47
Endemic in: Central & South America (humid, high-rainfall, acidic soil conditions).
Paracoccidioides brasiliensis
48
Mickey Mouse cap appearance (fewer buds).
Paracoccidioides brasiliensis
49
22°C: Mold phase → Glabrous to leathery, wrinkled, pink to brown colonies.
Paracoccidioides brasiliensis
50
Only dimorphic Penicillium spp.
Penicillium marneffei
51
Paracoccidioides brasiliensis 37°C (____ agar): Rapid conversion to yeast phase.
BHI blood
52
Opportunistic pathogen: Common in immunocompromised patients (AIDS, hematologic malignancies) in Southeast Asia.
Penicillium marneffei
53
Resembles Histoplasma capsulatum.
Penicillium marneffei
54
Mold phase → Green aerial hyphae, reddish-brown vegetative hyphae.
Penicillium marneffei
55
desert bumps also called ___
Erythema nodosum
56
valley fever is also called ___
erythema multiforme
57
Produces red diffusible pigment.
Penicillium marneffei
58
Antigen detection for Histoplasma capsulatum uses what specimen
blood, CSF, urine
59
Natural reservoir: Soil; also infects dogs and horses.
Blastomyces dermatitidis (Blastomycosis)
60
North American blastomycosis
Blastomycosis

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