Mycoplasma Flashcards
1
Q
Describe Mycoplasma Pneumoniae
A
No cell wall Single membrane with sterols and cholesterol Divides by binary fission Requires enriched media for growth Morphology: Fried egg
2
Q
What is P1 Protein?
A
Characteristic of Mycoplasma: binds to oligosaccharide recpetors -> sticks to cells for growth and replication
3
Q
How does M.Pneumoniae cause pathology?
A
Induces an inflammatory response like chlamydia
4
Q
What is the epidemiology of M.Pneumoniae?
A
Can cause CA-Pneuoniae
Spreads among family members
5
Q
What is the clinical presentation of mycoplasma?
A
HA, Fever, Malaise, Chills
Myalgia
Important: CXR results out of proportion to clinical presentation
6
Q
How is M.Pneumonia diagnosed?
A
CXR Cultures (10-14 days) Serology PCR COLD HEMAGGLUTININS= > Bind I Ag or erythrocytes @ 4degC
7
Q
How is M.Pneumoniae treated?
A
Macrolides: no cell wall!
Tetracyclines
Fluoroquinolones: Empiric therapy for pneumonia in general
No cell wall -> penicillins ineffective
