Myocardial Infarction Flashcards
(22 cards)
Irreversible MI damage happens when
20-40 minutes of MI
MI usually affects what chamber of the heart
Left ventricle
Causes of MI
- Atherosclerosis
- Vasospasm
- Decreased O2 supply
- Increased O2 demand
Ischemia meaning
Insufficient tissue oxygenation
Premature cell death
Necrosis
Blank cells/min if is blocked for blank
500 cells/min
>45 minutes
Death of tissues due to O2 deprivation
Infarction
What layer of the heart does infarction start
endocardial layer
Transmural Infarction
Necrosis extends through all layers of the myocardium
Small Damage transmural infarction
Dyskinetic - cannot contract in a coordinated manner
Extensive damage
Akinetic - unable to contract
Predisposing/Precipitating factors of MI
Stress Obesity DM and HTN Diet African American Age
Lab tests
Creatinine Kinase (CK-MB)
Myoglobin
Troponin
Heme protein that helps transport O2
myoglobin
Protein found in the myocardium; regulates myocardial contractile process
Troponin
3 isomers of Troponin
C, I, T
I, T - reliable and critical markers of myocardial injury
Immediate treatment for MI
MONA TASS
Medical Mgt Goals
- minimize myocardial damage
- preserve myocardial function
- prevent complications
ACE inhibitors function
Prevents conversion of angiotensin I to angiotensin II which is a potent vasoconstrictot
Thrombolytics function
- administered 3-6 hours
- initiated within 30 minute (door-to-needle time)
- dissolve thrombus
- allows reperfusion
Emergent Percutaneous Coronary Intervention
Cardiac catherization - procedure to open the occluded artery
How long should cardiac catheterization be performed
<60 minutes (door-to balloon time)
