N4 Flashcards
(53 cards)
structural causes of epilepsy
temporal sclerosis, cortical dysplasia, vascular malformations, TBI, cerebral, infarction, CNS tumors, infections
purpose of EEG in a patient with first unprovoked seizure
helps to stratify patient risk and the need for maintainence antiepileptic agents
patient with recurrent seizure activity
candidate for benzodiazepine or antiepileptic drugs
another name for IIH
indiopathic intracranial hypertension = pseudotumor cerebri
patient presentation for IIH
features of inc ICP in an alert patient, absence of focal neuro signs except for sixth nerve palsy, no ecidence for other causes of inc intracranial hypertension on neuroimaging, normal CSF exam except for inc CSF opening pressure
treatment goals for IIH
prevention of vision loss, surgical intervention with optic nerve sheath decompression or lumboperitoneal shunting
IIH patient requirement to prevent vision loss
fundoscopy and routine monitoring of visual acuity and visual fields
IIH may be caused by meds
tetracyclines, isotretinoin
first line treatment for IIH
acetazolamide
mechanism for acetazolamide in IIH
inhibits choroid plexus carbonic anhydrase - dec CSF production and IH
IIH patients on acetazolamide that are unresponsive
add furosemide
IIH pateints refractory to medical treatment
surgical intervention -optic nerve sheath decompression -lumboperitoneal shunting
IIH patients waiting for definitive surgical treatment
short term use of corticosteroids, serial LP, can serve as bridging therapy
patients on manitol require
careful monitoring of renal function and electrolytes
autism neuroimaging
inc total brain volume
OCD neuroimaging
abnormalities in orbitofrontal cortex and striatum (basal ganglia)
panic disorder neuroimaging
decreased volume of the amygdala (and left temporal lobe)
PTSD neuroimaging
dec hippocampal volume
schizophrenia neuroimaging
enlargement of cerebral ventricles esp lateral ventricular enlargement
after the diagnosis of MG is established, what should be ordered
CT of the chest - screen for thymoma if the pt is younger than 60
benefits of CT of the chest in an MG pt
thymectomy is mostly useful in such cases - results are seen 3-4 years after surgery
edrophonium test
less sensitive than MG antibodies and is difficult to interpret if the pt has only mild findings
anti Jo antibodies
polymyositis
anti RNP antibodies
MCTD