NA 1 Flashcards

1
Q

What are nucleic acids made out of

A

Nucleotides

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2
Q

Which organelles can contain their own genetic material

A

Mitochondria and chloroplasts

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3
Q

What is the biochemical role of NA

A

Store and transfer genetic material

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4
Q

T/F, the nucleus is a double-membrane organelle

A

True

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5
Q

What does the nucleus facilitate the movement of

A

RNAs, histones, and ribonucleoprotein particles

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6
Q

What is the general structure of a nucleotide

A

5-carbon, a nitrogenous base, 1-3 phosphate groups

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7
Q

What kind of bond is between the sugar and nitrogenous base

A

N-glycosidic bond

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8
Q

What attaches the sugar and phosphate group

A

Ester linkages

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9
Q

Whats the difference between nucleotide and nucleoside

A

Nucleosides don’t have phosphate groups

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10
Q

Fill in the blank: ribose sugars have a _______ attached to 2’-carbon

A

Hydroxy or OH

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11
Q

Fill in the blank: deoxyribose has a _________ attached to the 2’-carbon

A

Hydrogen or H

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12
Q

How many aromatic rings are there for purines

A

Two

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13
Q

How many fused aromatic rings are there for pyrimidines

A

1

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14
Q

Name purines

A

Adenine and guanine

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15
Q

Name pyrimidines

A

Cytosine, uracil, thymine

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16
Q

What endings do nucleosides have in nomenclature

A

-osine or -idine

17
Q

For nomenclature, what do nucleotides end in

A

Mono/di/triphosphate

18
Q

How do nucleotides connect to one another

A

By covalent phosphodiester bridges

19
Q

Why are covalent phosphodiester bridges negatively-charged

A

Because of phosphate groups

20
Q

In a nucleic acid chain, what is on the 5’ end

A

Phosphate group

21
Q

In a nucleic acid chain, what is on the 3’ end

A

Free hydroxyl group

22
Q

What is the most common type of dna damage

A

Single strand break

23
Q

What type of chromatin do human genomes primarily have

A

Euchromatin

24
Q

Which type of chromatin is less compacted and more frequently transcribed

A

Euchromatin

25
Q

What chromatin is more compacted and less frequently transcribed

A

Heterochromatin