Narcotics

Question 1

OPIOID NARCOTICS

Morphine, codeine, hydrocodone (vicodin), oxycodone, etc.

Answer 1

MECHANISM
React with endogenous opioid receptors.

INDICATIONS
Analgesia: Mod/Severe, acute or chronic pain.
Anti-tussive (cough)
Anti-diarrheal
Dyspnea associated with MI.

SIDE EFFECTS
Mental status changes including drowsiness.
Nausea/vomiting.
Constipation

ADVERSE EFFECTS
Postural hypotension
Respiratory depression
Tolerance leading to increased dosages
dependence and addiction
Withdrawl=nasty

Question 2

NON-OPIOID NARCOTICS

Acetominophen (Tylenol)

Answer 2

MECHANISM
Weak inhibitor of prostoglandins

INDICATIONS
Used for mild to moderate pain relief.
Antipyretic
NOT and anti-inflammatory

SIDE EFFECTS
Most are severe.
ADVERSE EFFECTS
In very large doses can cause liver damage.