Nasal polyp Flashcards
(35 cards)
Nasal polyp definition
Protrusions from edematous mucosa of paranasal sinuses
Types
- Antrochoanal
- Ethmoidal
Causes of bilateral nasal polyps in adults
- Allergy
- Aspirin exacerbated respiratory disease
- Eosinophilic granulamatosis with polyangitis/Chrug strauss syndrome
- Young’s syndrome
Causes of bilateral nasal polyp in children
- Cystic fibrosis
- Primary ciliary dyskinesia
Causes of unilateral nasal polyp in adults
- Chronic bacterial sinusitis
- Allergic fungal sinusitis
Samter’s triad
Aspirin hypersensitivity, Asthma, Nasal polyp
Young’s syndrome
Chronic sinusitis(+/- Nasal polyps), Brochiectasis, Azoospermia/Infertility
Churg Strauss syndrome age of onset
30 - 50 years
Presentation of churg strauss syndrome
Adult onset asthma
Systemic features: malaise, fever, weight loss, myalgia and polyarthralgia
Bilateral nasal polyps
Investigation for churg strauss syndrome
Peripheral eosinophils > 10%
Biopsy: Eosinophilic granulomas, Necrotizing vasculitis
Cystic fibrosis also known as
Mucoviscidosis
Pathophysiology of cystic fibrosis
Abnormal chloride channels
Clinical features of cystic fibrosis
Intestinal obstruction, Chronic sinusitis(Bilateral nasal polyps), Recurrent lung infections, Pancreatitis
Test for cystic fibrosis
Sweat chloride test > 70 meq/l
Primary ciliary dyskinesis also known as
Kartagener’s syndrome
Pathophysiology of PCD
Absence of ciliary movement
Clinical features of PCD
Chronic sinusits (+/- Nasal polyps), Bronchiectasis, Dextrocardia/situs inversus
Normal ciliary movement rate
Time taken to clear pharynx
5-10 mm/min, 10-20 min
Tests for mucociliary clearance
Invitro : Epithelial biopsy and study on electron microscope
In vivo : Saccharine test, Nuclear testing/Scintigraphy
CT finding of Allergic fungal sinusitis
Double density/rail track sign
Nasal polyp mimics
Concha bullosa
Meningocele
Meningoencephalocele
Glioma
Malignancy
Tests to differentiate encephalocele from nasal polyp
Frustenberg test
Transillumination test
Why is biopsy contraindicated in case of encephalocele
Biopsy can cause CSF leak
Management of nasal polyp
- Medical management : Steroid nasal spray, Saline nasal spray
- Surgical management (if medical management is ineffective after 1-2 months): Excision of nasal polyp + FESS
- Post operative management : Allergic fungal sinusitis : Steroid nasal spray, Antrochoanal polyp - No role of steroid