nasopharynx Flashcards

(57 cards)

1
Q

Nasopharynx is more common in

A

Asia, NA, Southern China

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2
Q

Age –more than __% are less than 55 y.o.

A

50%

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3
Q

Ratio men to women

A

2:1

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4
Q

Etiology

A

DIET - nitrates, EBV, poor ENT disease, dust inhalation

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5
Q

Anatomy of nasopharynx

A

nasal fossa, sup oropharynx, lat middle ears eustachian tubes, soft palate, lateral and postsup pharynxgeal wall, adenoid

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6
Q

Most common presenting symptom

A

painless upper neck mass

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7
Q

Clinical presentation

A

epistaxis, hearing/breathing problems, headache

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8
Q

__% present with neurologic symptoms

A

25

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9
Q

Cranial nerve involvement

A

V and VI

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10
Q

Otitis

A

ear pain

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11
Q

Extension into pre vertebral muscles involve
pain upon __ of the neck

A

extension

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12
Q

2 major routes for direct spread to the brain

A

foramen lacerum and ovale

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13
Q

nerve V

A

trigeminal

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14
Q

nerve VI

A

abducens

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15
Q

Most common histology

A

SCC/epidermoid

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16
Q

__% present distant mets

A

25

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17
Q

Mets to __ is most common

A

bone then liver then lungs

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18
Q

Lymphatic spread

A

node of rouvier to sup jugular and post cervical

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19
Q

post cervical nodes

A

spinal accessory nodes

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20
Q

node of rouvier

A

retropharyngeal

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21
Q

__-__% have positive cervical nodes

A

75-80

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22
Q

__-__% bilateral/contralateral have distant mets

A

40-70

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23
Q

First clinical indication of lymphatic spread will tend to be __ __nodes

A

jugulo digastric

24
Q

___ is close to carotid so
inaccessible surgically therefore must be
included in nasopharynx treatment volume

A

node of rouvier/retropharyngeal

25
__ is the first treatment of choice
rt
26
Energy preference
lower: superficial structures higher: disadvantage due to separation, sensitivity, surrounding OAR
27
sup border
2 cm margin beyond tumor, include base of skull and sphenoid sinuses
28
post border
2 cm magin beyond mastoid process
29
ant border
include post 1/3 maxillary sinus and nasal cavity
30
inf border
thyroid notch, spare larynx
31
treatment arrangement
opposed lateral field encompass tumor and nodal spread
32
dose
5000 cGy
33
CD boost
6500 cGy
34
dose with lymphadenopathy
7000
35
True/False: ANT Neck fields always incorporated in treating NP even with IMRT/3D with or without disease present
true
36
T1 T2 dose
60-70 Gy
37
T3 T4 dose
7000
38
side effects of radiation short term
skin change, nausea, vomiting, fatigue, mouth sore, hoarseness, loss of taste
39
long term rad side effect
xerostomia, tooth decay, bone damage, salivary gland damage, vision/hearing loss
40
chemo drug for naso
cisplatin
41
targeted therapy
erbitux
42
sore throat begins __ week RT
2
43
sore throat persists for __ post RT
1-2 months
44
TSH levels should be monitored every ___ ___
6-12 months
45
survival
45%
46
nasal vestibule
entrance to cavity, skin hair sweat glands
47
48
anatomy of nasal cavity
nasal vestibule limen nasi - beginning -paired nasal cavity sep by septal cartilage turbinates - bony folds
49
symtoms of nasal cavity cancer
Obstruction * Minor intermittent bleeding * Sinus trouble/discharge * Orbital invasion
50
spread of nasal cavity
direct, mid and inf turbinates
51
lymph spread nasal cavity __-__% at time of diagnosis
10-15
52
tx of nasla cavity
rt or surgery early lesion
53
papilloma tx
surgery
54
SCC or adeno tx nasal cavity
either or combo.. rt>surgery cosmesis
55
nasal cavity dose
60-65 in 6-7 weeks
56
survival nasal cavity
45-59%
57