Natural Hisotry Of Disease Flashcards

0
Q

When does the preclinical phase begin in that natural history of disease?

A

Biological onset of disease

Pathologic evidence

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1
Q

Prognosis

A

Prediction of probable cure & outcome of a disease

Likelihood of recovery from a disease

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2
Q

When does the clinical phase begin in the natural history of the disease?

A

Medical care
Diagnosis
Treatment
Outcome

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3
Q

What are five ways of expressing prognosis?

A
Case fatality rate
5 year survival rate
Observed survival rate
Median survival rate
Relative survival rate
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4
Q

In the 5 methods, what is the most accurate method?

A

Relative survival rate

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5
Q

Which prognosis method can we observe survival using life tables?

A

Observes survival rate

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6
Q

Which prognosis method is an age-adjustment for survival rates?

A

Relative survival rate

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7
Q

Which prognosis method is a measure of virulence?

A

Case fatality rate

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8
Q

Which prognosis method allows for calculation of only half the study population?

A

Median survival rate

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9
Q

Case fatality rate (CFR) formula

A
# of ppl who die from disease
----------------------------------
# of ppl w/disease
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10
Q

What does a CFR of 80% mean?

A

80% of ppl died from the disease out of the amount of ppl that had it

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11
Q

How do you calculate 5 year survival rate?

A

% of patients alive after 5yrs of treatment began

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12
Q

Is it possible to calculate 2 year survival rate?

A

Yes

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13
Q

What problem is associated with calculating 5 year survival and give example?

A

Screening, arbitrary, can miss ppl

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14
Q

What does the 5 year survival rate of 90% mean?

A

Treatment is very effective

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15
Q

What prognosis method improved upon the limitation of 5 year survival?

A

Observed survival

16
Q

What is the median survival time?

A

Length of time that half the study population survives

17
Q

Give two reasons why median survival time is preferred over mean survival time?

A

So data wouldn’t be screwed

Median is less effected

18
Q

How does it improve upon observed survival rates?

A

Calculates probability of surviving each year

When to expect it to go down

19
Q

Are survival data usually representative of the general pop? Why or why not?

A

No bc the data is often obtained from hospitals or other healthcare facilities
And patients may not be representative of the general pop