Nausea And Vomiting

Question 1

What drug is used for the prophylaxis for nausea and vomiting

Answer 1

Antihistamines (cyclizine and promethazine) or phenothiazines (prochlorperazine)

Question 2

What anti-emetic is given in pregnancy

Answer 2

Generally drug therapy should be avoided but use promethazine if needed

First line chlorperazine, cyclizine, prochlorperazzine, promethazine

Second line : doperidone ondansetron metoclopramide

Question 3

What anti-emetic is used in post-operations

Answer 3

5HT3-receptor antagonist (ondansetron) or dexamthasone

Cyclzine dexamethasone prochlorperazine prochlorperazine ondansetron, droperiodol

Question 4

What antiemetic is used for pre operations anticipatory

Answer 4

Lorazepam as short acting

Question 5

What ant-emetic is used for motion sickness

Answer 5

Hyoscine HYDRObromide
MRHA update- risk of severe anticholinergic side effects with hypscine bromide patches

Question 6

What anti-emetic is used for in terminal illness

Answer 6

Antipsychotic (haloperidol and levomepromazine, domperidone, metoclopramide. Levomepromazine, cyclizine, dexamethasone or hyoscine butyl bromide

Question 7

What anti emetic is used for in patients who have Parkinson’s

Answer 7

Domperidone

Question 8

What is domperidone

Answer 8

An anti-emetic that doesn’t cross the BBB therefore suitable for Parkinson’s disease

10mg three times a day

Minimum age is 12

Maximum use is 7 days

Patient should be 35+kg

Causes QT prolongation

Fun fact: mettoclopramide is same dose 10mg 3x a day

Question 9

What is metoclopramide

Answer 9

Does cross the BBB
Causes extra pyramidal side effects- do not use in Parkinson’s

10mg 3x a day
Minimum age is 18
Maximum use 5 days