NB1 Flashcards

(37 cards)

1
Q

What are neurons

A

Cells that transmit nerve impulses

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2
Q

What are glia

A

Non-neuronal cells in the central and peripheral nervous system that do not produce electrical impulses

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3
Q

What are microglia

A

Macrophages found in the brain and spinal cord

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4
Q

What consist of the central nervous system

A

Brain, brain stem, and spinal cord

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5
Q

What consist of the peripheral nervous system

A

All the nerves in the body that are found outside the spinal cord

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6
Q

What is the term for ribosomes in the cell body of a neurone

A

Nissl bodies

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7
Q

What is the term for cell body of a neurone

A

Perikaryon

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8
Q

Function of glial cells

A

-Provide structural support and myelin to the nervous system

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9
Q

Function of astrocytes

A

Provide structural support / blood brain barrier

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10
Q

Function of oligodendrocytes

A

Form myelin in central nervous system

Schwann cells in PNS

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11
Q

Function of ependymal cells

A

Line the ventricles and produce cerebrospinal fluid

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12
Q

Function of microglia

A

Macrophages of the brain (phagocytic)

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13
Q

Cells that give rise to brain tumours

A

Glial cells give rise to gliomas

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14
Q

What is the cerebrum

A
  • Consist of right and left cerebral hemisphere

- Has 4 lobes : Frontal, Parietal, Occipital, Temporal

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15
Q

What is the brainstem

A
  • Final part of brain before spinal cord begins

- Divided into 3 parts; (from top to bottom - Midbrain, Pons, Medulla)

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16
Q

What is the cerebellum

A

Posterior aspect of the brain/brainstem

17
Q

What does the hindbrain consist of

A

Pons, Medulla, Cerebellum

18
Q

What is grey matter

A

Neural tissue that is grey in colour and is comprised of neural cell bodies

19
Q

What is white matter

A

Neural tissue that is white in colour and is compromised of myelinated axon

20
Q

What is cortex

A

Outer layer of the cerebral hemispheres, composed of folds of grey matter

21
Q

What is gyrus

A

Convex fold of grey matter (mountains)

22
Q

What is sulcus

A

Concave folds of grey matter (valleys)

23
Q

What does association fibres do

A

Interconnect cortical sites within one cerebral hemisphere

24
Q

What does commissural fibres (corpus callosum) do

A

Run from one cerebral hemisphere to the other

25
What does projection fibres do
Pass from cerebral cortex to subcortical structures
26
Definition: 1. ipsilateral 2. contralateral 3. decussate
1. on the same side 2. on the opposite side 3. to switch from one side to another
27
What are cranial nerves
A set of 12 pairs of nerves that emerge directly from the brain
28
What are spinal nerves
Nerves that exit from the spinal cord (below brainstem)
29
Difference between afferent & efferent neurone
Afferent is a 3 neurone pathway while efferent is a 2 neurone pathway
30
Meningeal layers
``` Skin Bone -Dura mater -Arachnoid mater Subarachnoid space Trabeculae -Pia mater Blood vessel Cerebral cortex White matter ``` note: '-' are the actual meninges
31
What is pia mater (soft)
Very outer layer of brain tissue and intimately connected with the brain
32
What is arachnoid mater (spidery)
Thin, transparent tissue that covers brain specimen | Overlies sulcus
33
What is dura mater (hard)
Thick, fibrous connnective tissue associated with skull and form partitions between hemispheres
34
What does ectoderm, mesoderm and endoderm become
Ectoderm - all epidermis and nervous system Mesoderm - bone, muscle, connective tissue and dermis Endoderm - inner lining of GI tract; respiratory tract
35
Places in the embryonic disc that has ectoderm and endoderm only
1. Oropharyngeal membrane - dissolves; anterior is stomodeum which give rise to mouth 2. Cloacal membrane - posterior is proctodeum which gives rise to anus
36
What does neural crest cells contribute to
1. Neurons and glial cells of the sensory, sympathetic and parasympathetic nervous system 2. The epinephrine-producing (medulla) cells of the adrenal gland 3. The pigment-containing cells of the epidermis 4. Many of the skeletal and connective tissue components of the head
37
Describe zipping process
- Begins at day 22 - Tube close completely at the cranial end 3 or 4 days later and at the tail (caudal) end 2 to 3 days subsequently (day 27) - Neurulation is complete - CNS is a closed tube - narrow caudal end = spinal cord - Broader region at head region = brain