NBME2 Flashcards
All (20 cards)
Asbestos related disease
Most common lesions ?
Benign pleural plaques
ARE NOT PRECURSOR LESION FOR A MESOTHELIOMA
Most common asbestos related cancer
Bronchogenic carcinoma
NO ⬆️ risk for TB
Asbestos
Asbestos
Lung tissue bx ?
Ferruginous body
Carbon tetrachloride
Free radical : damage membranes and DNA (Hepatotoxicity)
Site for acetaminophen, CCl4, L-amanitin, Cu+ toxicity
Zone 3
Zone that undergo necrosis as a result of yellow fever
Zone 2
Capsaicin
⬇️ levels of substance P
Analgesic ^ antiinflammatory
Arthritis ^ neuralgia
TTP
Clinical pentad ?
Fever Thrombocytopenia Renal failure Microangiopathic hemolytic anemia (schistocytes) CNS deficits
Prevalence
Formula?
Prevalence = incidence * duration of the disease
NK activity
enhanced by ?
Express ?
- IL2, IFN ALFA, IFN BETA
2. CD16, CD 56
How C perfringens evades destruction by neutrophils in pts w/clostridial myonecrosis?
Damaging neutrophil membranes by means of a membrane-damaging toxin (alpha toxin aka phospholipase)
Carboxylase deficiency
Ataxia, hypotonia, hearing loss, hair loss, rash
Biotin: cofactor for carboxylation enzymes
EB virus initially replicates in which type of cells ?
Pharyngeal B lymphocytes
Effect of cirrhosis
Portal HTN
Free radicals
Lipid peroxidation of membranes
Serous or blood nipple discharge
Intraductal papilloma
1.5 - 2 x ⬆️ risk for carcinoma
Bronchial asthma
Eosinophil product responsible for damage to the epithelium ?
Major basic protein
Cationic protein
45yo woman. Skin of her feet pink, dry, hot
Which fiber is most likely to be disrupted?
Postganglionic sympathetic
Enzyme involved in production of 5-HPETE ^ Leukotrienes ?
5- lipoxygenase
