Neck lumps Flashcards

(36 cards)

1
Q

Characteristics of a lump

A

4S: Site, size, shape, sound

4T: Temperature, tenderness, transillumination, tethering/mobility

4C: Contour, consistency, colour, compression

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2
Q

Borders of the anterior triangle of the neck

A

Midline, mandible, sternocleidomastoid

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3
Q

Borders of the posterior triangle of the neck

A

Sternocleidomastoid, clavicle, anterior margin of the trapezius

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4
Q

Lymph node compartments/levels of the neck

A
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5
Q

DDx of pulsatile masses in the anterior triangle

A

Carotid body tumour

Carotid artery aneurysm

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6
Q

DDx of non-pulsatile masses in anterior triangle

A

Midline:

  • Thyroglossal cyst (moves upwards with tongue)
  • Dermoid cyst (non-mobile)
  • Chondroma

Non-midline:

  • Goitre (may be retrosternal, may be uni/multinodular, may have bruits)
  • Branchial cyst
  • Laryngeocoele
  • Pharyngeal pouch
  • Lymphadenopathy
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7
Q

DDx of posterior triangle masses

A

Malignancy until proven otherwise!

Reactive lymphadenopathy

Pharyngeal pouch

Lymphoma

Cervical rib

Cystic hygroma

Subclavian aneurysm

Pancoast’s tumour

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8
Q

Features of hyperthyroidism

A

Sweating

Weight loss/weakness (proximal myopathy)

Emotional lability

Appetite increased

Tremor/tachycardia

Irritability, irregular mensturation, intolerance of heat

Nodules/goitre

GI problems (diarrhoea)

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9
Q

Common causes of hyperthyroidism (overactive thyroid gland)

A

Graves’ (autoimmune)

Toxic multinodular goitre/solitary adenoma

Amiodarone (high I2 content)

High beta-HCG (pregnancy, hydratiform mole)

Pituitary adenoma

Follicular thyroid cancer

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10
Q

Causes of thyrotoxicosis (not necessarily overactive thyroid gland, detected by reduced I2 uptake)

A

Hyperthyroidism

De Quervain’s thyroiditis (followed by hypothyroidism, self-limiting)

Supre-therapeutic Levothyroxine

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11
Q

Features of Graves’ disease

A

Lid lag

Exophthalmos

Chemosis

Bruits

Smooth uniform goitre

Reduced eye movements

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12
Q

Features of hypothyroidism

A
  • Symptoms
    • Weight gain
    • Low mood
    • Tiredness
    • Amennorhea/menstrual distrubances
    • Cold sensitivity
    • Hoarseness
    • Memory impairment
  • Signs
    • Bradycardia
    • dry skin
    • Hair loss (outer 1/3 of eyebrows)
    • Coarse facial features
    • Malar flush
    • Painless goitre
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13
Q

Causes of hypothyroidism

A

Autoimmune: Hashimoto’s (most common!)

Iatrogenic: Radiation, drugs (amiodarone, lithium, carbimazole)

Other: Iodine deficiency, post-partum, congenital

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14
Q

DDx of parotid lump

A

Parotitis

Salivary gland tumour

Stone

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15
Q

DDx of lateral neck lump

A

Artery: Carotid aneurysm, carotid body tumour, subclavian aneurysm

Lymph nodes: Infective, malignant, granulomatous

Nerve: Neurofibroma, schwannoma

Larynx: Laryngocoele

Pharynx: Pharyngeal pouch

Branchial: Cyst/sinus/fistula

Skin: Lipoma, epidermal cyst, abscess

Musculoskeletal: Cervical rib, sarcoma

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16
Q

Most common causes of neck lumps in children

A

75% benign causes (congenital malformations, inflammatory lymphadenitis)

17
Q

Most common causes of neck lumps in adults

A

75% malignant (80% mets, 20% lymphomas)

18
Q

Painful neck lumps

A

Infective lymphadenitis

Infected branchial cyst

19
Q

How does duration of neck lump presence change differential?

A

<few weeks:> Infective/inflammatory lymphadenopathy (NB: may be ‘suddenly’ notice by patient)</few>

>few weeks: Must exclude malignancy

Years: Benign most likely

20
Q

DDx if lumps present elsewhere

A

Disseminated malignancy (e.g. lymphoma)

Systemic disease (e.g. EBV, HIV)

21
Q

Hx questions for neck lumps

A

Recent infection/contact with infected person

Symptoms of head/neck cancer: Voice/swallowing changes, inspiratory noises/difficulty breathing, hearing loss/otalgia

Radiotherapy of neck

Smoking/alcohol intake

22
Q

DDx of superficial neck lumps

A

Lipomas, abscesses, epidermal/dermoid cysts

23
Q

Associated symptoms of pharyngeal pouch

A

halitosis, dysphagia, gurgling on palpation, chronic cough

24
Q

How to examine relationship of lump to muscle

A

Ask pt to nod head against resistance (SCM) or shrug shoulder against resistance (trapezius)

Deep to muscle –> concealed

25
Effect of malignancy on lymph node texture + tethering
Malignant lymph nodes may be tethered to adjacent structures + are hard
26
Differentiating finding of benign vs malignant parotid tumour
Facial nerve palsy in malingnant but not benign
27
Differential for thyroid lumps in order of commonality
Physiological goitre Multinodular goitre Graves' disease Hashimoto's thyroiditis Thyroglossal cyst Solitary adenoma Carcinoma Subactue thyroiditis (e.g. de Quervain's)
28
Risk factors for thyroid malignancy
Age \<20 or \>70 Radiation of neck FHx of thyroid malignancy/endocrine neoplasias Rapid growth/compression symptoms Firm, hard nodule **Cervical lymphadenopathy**
29
Thyroid status in thyroid malignancy
Almost always euthyroid
30
Clinical features of EBV infx
Sore throat Swollen tonsils Lymphadenopathy Splenomegaly Fever
31
Effect of smoking in Graves disease
Increase risk of eye signs (specific to Grves)
32
Turner's syndrome is a risk factor for which neck lump?
Cystic hygromas
33
Sjogren's is a risk factor for which neck lump
Non-Hodgkin lymphoma
34
Pathophysiology of Graves
Autoantibodies to TSH receptor --\> hyperthyroidism (antibody-mediated stimulation)
35
Pathophysiology of Hashimoto's
T-cell mediated destruction of thyroid cells --\> hypothyroidism
36
Types of thyroid malignancy in order of prevalence
Papillary Follicular Medullary Lymphoma Anaplastic *Please FML...*