Necrobiosis Lipoidica

Question 1

What percentage of patients with Diabetes have NL ?

Answer 1

0.3%

Question 2

True or false

There is a proven connection between a patient’s level of glycemic control and the likelihood of developing NL lesions.

Answer 2

False

There is NO proven connection between a patient’s level of glycemic control and the likelihood of developing NL lesions.

Question 3

If a diabetic patient has NL , what doesthat mean for him ?

Answer 3

diabetic patients with NL do appear to have a higher rate of diabetes-related complications such as peripheral neuropathy, retinopathy and limited joint mobility

Question 4

What is the typical age of onset for NL ?

F:M ratio ?

Answer 4

For DM : 25
For non DM : 46
F:M = 3:1

Question 5

what is the characteristic histopathology of NL ?

Answer 5

Palisading granulomatous dermal inflammation composed of epithelioid histiocytes surrounds degenerated collagen.
The infiltrate in dermis is diffuse / full thickness.
Epidermis is normal or atrophic

Question 5

what is the characteristic histopathology of NL ?

Answer 5

Palisading granulomatous dermal inflammation composed of epithelioid histiocytes surrounds degenerated collagen.
The infiltrate in dermis is diffuse / full thickness.
Epidermis is normal or atrophic

Question 6

what proportion of people with NL have diabetes mellitus ?

Answer 6

15-65%